Tympanic membrane retractions in patients with Williams Syndrome : a controlled study
| Autor: | Marcel Machado Valério, Têmis Maria Félix, Joel Lavinsky, Marcelo Wierzynski de Oliveira, Luiz Lavinsky |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Williams syndrome Chronic otitis elastin macromolecular substances Otite média Original research Membrana timpânica Tympanic membrane retraction 03 medical and health sciences 0302 clinical medicine Ophthalmology Síndrome de Williams Medicine In patient Chronic otitis media 030223 otorhinolaryngology Original Research williams syndrome Pars tensa biology business.industry digestive oral and skin physiology medicine.disease humanities Elastin Otorhinolaryngology RF1-547 chronic otitis media 030220 oncology & carcinogenesis biology.protein Pars flaccida business Elastina |
| Zdroj: | Repositório Institucional da UFRGS Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS International Archives of Otorhinolaryngology, Vol 25, Iss 03, Pp e443-e445 (2021) International Archives of Otorhinolaryngology v.25 n.3 2021 International Archives of Otorhinolaryngology Fundação Otorrinolaringologia (FORL) instacron:FORL International Archives of Otorhinolaryngology, Volume: 25, Issue: 3, Pages: 443-445, Published: 13 SEP 2021 |
| Popis: | Introduction The role of elastin in tympanic retractions and chronic otitis media is not well established. Williams Syndrome (WS), a pathology related to a mutation in the elastin gene, could generate tympanic retractions. Objective To compare the prevalence of tympanic retractions among patients with WS and controls. Methods WS patients (n = 43 ears) and controls (n = 130 ears) were evaluated by digital otoscopic examination and the degree of tympanic membrane retraction was classified by 2 blinded experienced otolaryngologists. Results The agreement rate between the evaluators was 71.1% for pars tensa and 65% for pars flaccida retraction (p Conclusions Tympanic membrane retractions are not more common in the WS group when compared with controls. |
| Databáze: | OpenAIRE |
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