Outcomes of Reflex Cryptococcal Antigen (CrAg) Screening in Human Immunodeficiency Virus (HIV)-Positive Patients With CD4 Counts of 100–200 Cells/µL in Botswana

Autor:	Christopher G Williams, Leabaneng Tawe, Alexander Jordan, Julia Ngidi, Joseph N Jarvis, Gregory S. Greene, Leah Owen, Tshepo B Leeme, Tom Chiller, Madisa Mine, Thandi Milton, Charles Muthoga, Amber Boose, Ikanyeng Rulaganyang, Mark W Tenforde
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	0301 basic medicine Microbiology (medical) Antigens Fungal Cryptococcal antigen 030106 microbiology Human immunodeficiency virus (HIV) HIV Infections Meningitis Cryptococcal medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) Reflex medicine Humans Mass Screening 030212 general & internal medicine Botswana AIDS-Related Opportunistic Infections business.industry HIV medicine.disease Antiretroviral therapy Virology CD4 Lymphocyte Count Cryptococcus Infectious Diseases Brief Reports business
Zdroj:	Clin Infect Dis
ISSN:	1058-4838
Popis:	Increasing the CD4-count threshold for cryptococcal antigen (CrAg) screening from ≤100 to ≤200 cells/µL resulted in a 3-fold increase in numbers screened. CrAg-prevalence was 3.5% at CD4 101–200 and 6.2% ≤100 cells/µL. Six-month mortality was 21.4% (9/42) in CrAg-positive CD4 ≤100 cells/µL and 3.2% (1/31) in CrAg-positive CD4 101–200 cells/µL.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4def8fe550da45016b3c326474e37098 https://europepmc.org/articles/PMC8096249/ Zobrazit plný text záznamu