Preferential Aggregation of Obsessive—Compulsive Spectrum Disorders in Schizophrenia Patients with Obsessive—Compulsive Disorder
| Autor: | Artashez Pashinian, Ronit Weizman, Camil Fuchs, Victoria Kriss, Michael Poyurovsky, Sarit Faragian, Gregory Weisman, Abraham Weizman |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Obsessive-Compulsive Disorder medicine.medical_specialty Psychosis Comorbidity Severity of Illness Index behavioral disciplines and activities Obsessive compulsive mental disorders Severity of illness Prevalence medicine Humans Somatoform Disorders Psychiatry Obsessive–compulsive spectrum Mood Disorders medicine.disease Anxiety Disorders Diagnostic and Statistical Manual of Mental Disorders Psychiatry and Mental health Schizophrenia Anxiety Female medicine.symptom Psychology Anxiety disorder Clinical psychology |
| Zdroj: | The Canadian Journal of Psychiatry. 51:746-754 |
| ISSN: | 1497-0015 0706-7437 |
| Popis: | Objective: To validate a complex association between schizophrenia and obsessive–compulsive disorder (OCD). Method: We used the Structured Clinical Interview for DSM-IV Axis I disorders to compare the rate of OCD spectrum and additional Axis I disorders in 100 patients who met criteria for both schizophrenia and OCD, non-OCD schizophrenia ( n = 100), and OCD ( n = 35). Results: There was a robust between-group difference in the number of patients with one or more OCD spectrum disorders (schizo-obsessive n = 30, compared with schizophrenia n = 8; P = 0.001), that is, higher rates of body dysmorphic (8% compared with 0%) and tic (16% compared with 4%) disorders. No difference was revealed in affective, anxiety, and substance use disorders. We found comparable rates of OCD spectrum disorders in the schizo-obsessive and OCD groups (30% and 42.8%, respectively; P = 0.32). Conclusion: Preferential aggregation of OCD spectrum disorders in the schizo-obsessive group supports this unique clinical association. Whether a schizo-obsessive interface represents comorbidity or a specific subtype of schizophrenia warrants further investigation. |
| Databáze: | OpenAIRE |
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