Multiple Desmoplastic Cellular Neurothekeomas in Child: Report of the First Oral Case and Review of the Literature
| Autor: | Jorge Esquiche León, Lana Kei Yamamoto Almeida, Luciana Yamamoto Almeida, Ana Terezinha Marques Mesquita, Saulo Gabriel Moreira Falci, Cássio Roberto Rocha dos Santos, Tatiana Fernandes Araújo Almeida, Flaviana Dornela Verli |
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| Přispěvatelé: | Universidade Federal de Viçosa (UFV), Universidade de São Paulo (USP), Universidade Estadual Paulista (Unesp) |
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Cellular neurothekeoma
Pathology medicine.medical_specialty CD34 Vimentin Histogenesis Neurothekeoma Pathology and Forensic Medicine Neoplasms Multiple Primary 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Biomarkers Tumor medicine Humans Desmoplastic cellular neurothekeoma Child Original Paper biology medicine.disease Immunohistochemistry Oral cavity stomatognathic diseases Oncology Otorhinolaryngology Giant cell 030220 oncology & carcinogenesis biology.protein Female Mouth Neoplasms Differential diagnosis Epithelioid cell |
| Zdroj: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| Popis: | Made available in DSpace on 2018-12-11T17:12:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-03-01 Cellular neurothekeomas (CNs) are distinctive benign tumors of uncertain histogenesis, with predilection for the skin of the head and neck region. We describe the first case of multiple desmoplastic CNs (DCNs) affecting the oral cavity in a 9-year-old girl. Histopathologic evaluation showed a proliferation of spindle and epithelioid cells, forming nests and bundles, supported by exuberant fibrous stroma, as well as scattered multinucleated floret-like giant cells. The tumor cells were immunopositive for vimentin, CD63, CD56, whereas AE1/AE3, S100, CD34, α-SMA, GFAP, EMA, CD57 and NSE were negative. Ki-67 was |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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