Seropositivity of Chlamydophila pneumoniae immunoglobulin G antibody of HIV/AIDS patients in Abuja, Nigeria
| Autor: | US Inyang, Boyi Ngwai Yakubu, D. Ishaleku, IG Ijele, KS Izebe |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Medicine(all)
medicine.medical_specialty Chlamydia biology AIDSNigeria business.industry General Medicine Chlamydophila pneumoniae medicine.disease medicine.disease_cause Antibodies Immunoglobulin G Blood serum Acquired immunodeficiency syndrome (AIDS) Epidemiology Immunology medicine biology.protein Seroprevalence Antibody business |
| Zdroj: | Asian Pacific Journal of Tropical Medicine. 3(8):666-668 |
| ISSN: | 1995-7645 |
| DOI: | 10.1016/s1995-7645(10)60160-5 |
| Popis: | Objective: To detect IgG antibody to Chlamydophila pneumoniae (CP) in sera of HIV / AIDS patients and provide rationale for inclusion of routine screening for anti-CP antibodies and anti-chlamydial agents in the Nigerian National HIV / AIDS Management Plan. Methods: Serum samples from 34 consenting HIV/AIDS patients attended a Government-approved Antiretroviral Treatment Facility in Abuja were screened by enzyme-linked immunosorbent assay for anti-CP IgG antibody using ImmunoComb Chlamydia Bivalent IgG Test kit (Orgenics Israel). Results: Anti-CP IgG antibody was detected in 20 (58.8%) of 34 patients tested. The detection rate was higher among the males (8/13; 61.5%) than the females (12/21; 57.1%). Patients of the age group 16-30 years had the highest (7/10; 70%) detection of anti-CP IgG antibody. Conclusions: The result of the present study suggests the presence of anti-CP antibodies in sera of the HIV/AIDS patients and reinforces the need for routine screening for anti-CP antibodies as a necessary intervention to reduce the burden of Chlamydophila pneumoniae (C. pneumoniae) infections and to reduce HIV-positive morbidity in Nigeria. The outcome of this study also provides justification for the possible inclusion of anti-chlamydial agents in the National HIV/AIDS Management Plan to provide prophylaxis against or treat active C. pneumoniae infections. |
| Databáze: | OpenAIRE |
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