Effects of Percutaneous Transluminal Angioplasty of Superficial Femoral Artery on Photoplethysmographic Pulse Transit Times
Autor: | Niku Oksala, Jarmo Verho, Mikko Peltokangas, Antti Vehkaoja, Velipekka Suominen, Pekka Romsi, Janne Korhonen, Jukka Lekkala, Ville M. Mattila, Damir Vakhitov |
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Přispěvatelé: | Tampere University, Faculty of Biomedical Sciences and Engineering, Research group: Sensor Technology and Biomeasurements (STB), Verisuoni- ja toimenpideradiologinen keskus, Department of Musculoskeletal Diseases, Faculty of Medicine and Life Sciences |
Rok vydání: | 2019 |
Předmět: |
Adult
Male medicine.medical_specialty Percutaneous 0206 medical engineering Health Informatics Transit time 02 engineering and technology Pulse Wave Analysis 030204 cardiovascular system & hematology Transluminal Angioplasty Fingers Peripheral Arterial Disease 03 medical and health sciences 0302 clinical medicine Health Information Management Internal medicine medicine Humans Electrical and Electronic Engineering Photoplethysmography Aged Peripheral artery disease medicine.diagnostic_test business.industry Pulse (signal processing) Angioplasty Signal Processing Computer-Assisted 217 Medical engineering Index finger Middle Aged Toes Atherosclerosis 020601 biomedical engineering Computer Science Applications Femoral Artery body regions medicine.anatomical_structure Blood pressure Pulse wave measurements Cardiology Upper limb Female business Electrocardiography |
Zdroj: | IEEE Journal of Biomedical and Health Informatics. 23:1058-1065 |
ISSN: | 2168-2208 2168-2194 |
Popis: | We analyze the changes in upper and lower limb pulse transit times (PTT) caused by peripheral artery disease (PAD) and its treatment with percutaneous transluminal angioplasty (PTA) of the superficial femoral artery. PTTs were extracted from the photoplethysmograms (PPG) recorded from an index finger and 2nd toes. PTTs were defined between the R-peaks of the ECG and different reference points of the (PPG): foot and peak points, maxima of 1st and 2nd derivative, and by means of intersecting tangents method. Also the PTTs between the toe and finger pulses were analyzed. Our sample consists of 24 subjects examined before and after the PTA and in 1-month follow-up visit. Also 28 older than 65 years controls having normal ankle-to-brachial pressure index (ABI) and no history in cardiovascular diseases as well as 21 younger subjects were examined. The differences between the groups and pre- and post-treatment phases were analyzed by means of non-parametric statistical tests. The changes in the PTTs of upper limb and non-treated lower limb were negligible. The agreement with the reference values, ABI and toe pressures, was studied by kappa-analysis, resulting in kappa-values of 0.33- 0.91. Differences in PTTs were found between pre-treatment state of the treated limb, post-treatment state and the follow-up visit, as well as between the pre-treatment state and controls. If patients' age and systolic blood pressure were taken into consideration, the method of lower limb PTT calculation from the peak point turns out feasible in finding the markers of PAD and monitoring post- treatment vascular remodellation. acceptedVersion acceptedVersion |
Databáze: | OpenAIRE |
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