Partial-field illumination ophthalmoscope: improving the contrast of a camera-based retinal imager
| Autor: | Serge Meimon, Léa Krafft, Michel Paques, Laurent M. Mugnier, Yann Lai-Tim, Pedro Mecê, Elena Gofas-Salas, Olivier Thouvenin |
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| Přispěvatelé: | DOTA, ONERA, Université Paris Saclay [Châtillon], ONERA-Université Paris-Saclay, Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), Institut de la Vision, Centre National de la Recherche Scientifique (CNRS)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Langevin - Ondes et Images (UMR7587) (IL), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), ANR-18-CE19-0010,EyeWin,L'oeil, une fenêtre ouverte sur le couplage neuro-vasculaire(2018), ANR-15-RHUS-0001,LIGHT4DEAF,ECLAIRER LA SURDITÉ : UNE APPROCHE HOLISTIQUE DU SYNDROME D'USHER(2015), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPC) |
| Rok vydání: | 2021 |
| Předmět: |
Optics and Photonics
Microscope Laser scanning Computer science media_common.quotation_subject FOS: Physical sciences Signal-To-Noise Ratio 01 natural sciences Signal Retina law.invention 010309 optics Contrast Sensitivity 03 medical and health sciences [SPI]Engineering Sciences [physics] 0302 clinical medicine Optics law 0103 physical sciences Photography Contrast (vision) Humans Electrical and Electronic Engineering Adaptive optics Engineering (miscellaneous) Lighting media_common [PHYS]Physics [physics] Spatial filter Pixel business.industry Ophthalmoscopes Equipment Design Physics - Medical Physics Atomic and Molecular Physics and Optics 030221 ophthalmology & optometry Medical Physics (physics.med-ph) business Optics (physics.optics) Physics - Optics |
| Zdroj: | Applied optics. 60(31) |
| ISSN: | 1539-4522 |
| Popis: | Effective and accurate in-vivo diagnosis of retinal pathologies requires high performance imaging devices, combining a large field of view and the ability to discriminate the ballistic signal from the diffuse background in order to provide a highly contrasted image of the retinal structures. Here, we have implemented the Partial-Field Illumination Ophthalmoscope, a patterned illumination modality, integrated on a high pixel rate adaptive optics full-field microscope. This non-invasive technique enables us to mitigate the low signal-to-noise ratio, intrinsic of full-field ophthalmoscopes, by partially illuminating the retina with complementary patterns to reconstruct a wide field image. This new modality provides an image contrast spanning from the full-field to the confocal contrast, depending on the pattern size. As a result, it offers various trade-offs in terms of contrast and acquisition speed, guiding the users towards the most efficient system for a particular clinical application. 6 pages, 5 figures |
| Databáze: | OpenAIRE |
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