Cerebrospinal Fluid Iron‐Ferritin Ratio as a Potential Progression Marker for Parkinson's Disease

Autor:	Inga Zerr, Fabian Maass, Paul Lingor, Bernhard Michalke, Sezgi Canaslan, Mathias Bähr, Matthias Schmitz, Desiree Willkommen
Rok vydání:	2021
Předmět:	medicine.medical_specialty Parkinson's disease Protein biomarkers Iron cerebrospinal fluid [Iron] 03 medical and health sciences 0302 clinical medicine Cerebrospinal fluid cerebrospinal fluid [Parkinson Disease] Internal medicine medicine cerebrospinal fluid [Ferritins] Humans ddc:610 030304 developmental biology 0303 health sciences biology business.industry Iron levels Neurodegeneration Parkinson Disease medicine.disease Ferritin Endocrinology cerebrospinal fluid [Biomarkers] Neurology Ferritins biology.protein Neurology (clinical) business diagnosis [Parkinson Disease] Biomarkers 030217 neurology & neurosurgery
Zdroj:	Movement disorders 36(12), 2967-2969 (2021). doi:10.1002/mds.28790
ISSN:	1531-8257 0885-3185
DOI:	10.1002/mds.28790
Popis:	Longitudinal PD CSF samples were subjected to ICP-MS and the total amount of iron and other bioelements was quantified. Additionally, ferritin and protein biomarkers of neurodegeneration were measured. Over time, mean iron levels significantly increased while levels of ferritin decreased.
Databáze:	OpenAIRE
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