Corneal deposits after the topical use of ofloxacin in two children with vernal keratoconjunctivitis
| Autor: | Françoise Meire, Tineke N. Decaestecker, J-P Remon, Ph Kestelyn, Ilse Claerhout, J. Van Bocxlaer |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
Letter genetic structures Side effect business.industry Corneal Diseases corneal ulcer medicine.disease eye diseases Sensory Systems Ciprofloxacin Cellular and Molecular Neuroscience Ophthalmology medicine Prednisolone sense organs Ofloxacin business Vernal keratoconjunctivitis Norfloxacin medicine.drug |
| Zdroj: | British Journal of Ophthalmology. 87:646-646 |
| ISSN: | 0007-1161 |
| DOI: | 10.1136/bjo.87.5.646 |
| Popis: | Topical fluoroquinolones are broad spectrum, bactericidal agents with activity against both Gram positive and Gram negative corneal pathogens. Single drug administration with topical fluoroquinolones has been effectively used in treatment of bacterial ulcerative keratitis. The drugs are safe, but a white crystalline deposit, that in most cases spontaneously dissolved, has been reported1–4 with ciprofloxacin 0.3% and norfloxacin 0.3%. Up to now this side effect has not been described with ofloxacin 0.3%. We present two children with severe vernal conjunctivitis who developed corneal deposits after use of ofloxacin 0.3% eye drops. ### Patient 1 A 6 year old boy with vernal keratoconjunctivitis (VKC) developed a painful right eye while on holiday. His ophthalmologist diagnosed a corneal ulcer and prescribed ofloxacin eye drops followed by ofloxacin ointment four times a day for 3 weeks, associated with prednisolone drops. As the inflammation in the right eye persisted, the child was referred to our department. Slit lamp examination revealed mild VKC and a corneal ulcer with a … |
| Databáze: | OpenAIRE |
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