Inflammatory Breast Cancer and Warm Antibody Autoimmune Hemolytic Anemia: A Rare Paraneoplastic Syndrome

Autor: Chidinma Onweni, Sowminya Arikapudi, Jennifer Treece, Evan Kulbacki, Nene Ugoeke, Kailash Bajaj, Vandana Pai
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Journal of Investigative Medicine High Impact Case Reports, Vol 5 (2017)
Journal of Investigative Medicine High Impact Case Reports
ISSN: 2324-7096
Popis: Autoimmune hemolytic anemia (AIHA) is a disease process that involves the destruction of red blood cells mediated by the humoral immune system. It can be characterized as a cold agglutinin syndrome, paroxysmal cold hemoglobinuria, and warm, mixed type, and drug-induced AIHA. Although a well-established relationship exists between the presence of AIHA and lymphoproliferative malignancy, AIHA rarely presents in association with solid malignancies. An analysis of the limited number of published cases of AIHA in association with solid malignancies performed showed that AIHA may present before the diagnosis of a solid malignancy, concurrently with the presence of a solid malignancy, or even on resolution of a solid malignancy. Few cases of solid cancers associated with AIHA have been reported. AIHA rarely presents as a paraneoplastic syndrome indicating existence of a solid cancer. We report a case of inflammatory breast cancer with AIHA.
Databáze: OpenAIRE