Prevention of secondary osteoporosis postmenopause in hemiplegia
| Autor: | Chieko Hasegawa, Sang Soo Eun, Satoshi Miyano, Tetsuo Ikai, Mikumo Uematsu, Chiko Kimura |
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| Rok vydání: | 2001 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty Bone density Osteoporosis Osteocalcin Physical Therapy Sports Therapy and Rehabilitation Hemiplegia Alkaline phosphatase blood Absorptiometry Photon Bone Density Activities of Daily Living medicine Humans Amino Acids Radionuclide Imaging Geriatric Assessment Osteoporosis Postmenopausal Aged business.industry Rehabilitation Follow up studies ácido etidrónico Etidronic Acid Etidronic acid medicine.disease Alkaline Phosphatase eye diseases nervous system diseases body regions Menopause Physical therapy Disease Progression Female Secondary osteoporosis business medicine.drug Follow-Up Studies |
| Zdroj: | American journal of physical medicinerehabilitation. 80(3) |
| ISSN: | 0894-9115 |
| Popis: | To study secondary osteoporosis postmenopause in women with hemiplegia and to show the therapeutic effects of etidronate and how osteoporotic conditions relate to the activities of daily living (ADL).Eighty-one postmenopausal women with hemiplegia were admitted within 6 mo of their first cerebrovascular accident. The bone mineral density (BMD) and biochemical markers of bone turnover were measured at the time of admission. Forty women (treatment group) received a 2-wk administration of etidronate. Forty-one women (control group) were not administered etidronate.After completing a 3-mo rehabilitation program, BMD levels were remeasured. ADL was evaluated by FIM. The low ADL group had a larger decrease in BMD than the high ADL group. For the control group, the BMD rate of change on the paretic side of the femoral neck was -9.6%/3 mo for the low ADL group. BMD loss was reduced significantly by the administration of etidronate for the low ADL group.Results indicate that ADL corresponds to the progression of osteoporosis in postmenopausal women with hemiplegia and that increasing the level of ADL will reduce the progression of osteoporosis. Use of etidronate has also been proven to have a suppressive effect on the BMD decrease in women. |
| Databáze: | OpenAIRE |
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