Production of bacterial cellulose tubes for biomedical applications: Analysis of the effect of fermentation time on selected properties
Autor: | María Laura Foresti, G Villoldo, M S Pérez, A Sordelli, Patricia Cerrutti, L A Martínez, D R Corzo Salinas, Celina Raquel Bernal |
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Rok vydání: | 2021 |
Předmět: |
Male
Materials science Swine Biomedical Technology Fibril Biochemistry chemistry.chemical_compound Bioreactors Structural Biology Tensile Strength Specific surface area Spectroscopy Fourier Transform Infrared Animals Humans Water holding capacity Thermal stability Biomass Rats Wistar Cellulose Chemical purity Molecular Biology Cells Cultured Gluconacetobacter xylinus Stem Cells General Medicine Adipose Tissue chemistry Chemical engineering Bacterial cellulose Fermentation Thermodynamics Rabbits |
Zdroj: | International Journal of Biological Macromolecules. 189:1-10 |
ISSN: | 0141-8130 |
DOI: | 10.1016/j.ijbiomac.2021.08.011 |
Popis: | Biosynthesis of bacterial cellulose (BC) in cylindrical oxygen permeable molds allows the production of hollow tubular structures of increasing interest for biomedical applications (artificial blood vessels, ureters, urethra, trachea, esophagus, etc.). In the current contribution a simple set-up is used to obtain BC tubes of predefined dimensions; and the effects of fermentation time on the water holding capacity, nanofibrils network architecture, specific surface area, chemical purity, thermal stability, mechanical properties, and cell adhesion, proliferation and migration of BC tubes are systematically analysed for the first time. The results reported highlight the role of culture time on key properties of the BC tubes produced, with significant differences arising from the denser and more compact fibril arrangements generated at longer fermentation intervals. |
Databáze: | OpenAIRE |
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