Nasalization of Central Retinal Vessel Trunk Predicts Rapid Progression of Central Visual Field in Open-Angle Glaucoma
| Autor: | Youn Hye Jo, Kilhwan Shon, Daun Jeong, Joong Won Shin, Junki Kwon, Michael S. Kook |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
genetic structures Open angle glaucoma lcsh:Medicine Glaucoma Article Nasalization 03 medical and health sciences Medical research 0302 clinical medicine Ophthalmology medicine Humans Central visual field lcsh:Science Multidisciplinary business.industry lcsh:R Retinal Vessels medicine.disease Trunk eye diseases Ganglion Visual field Retinal vessel medicine.anatomical_structure Outcomes research Disease Progression Quality of Life 030221 ophthalmology & optometry Visual Field Tests lcsh:Q sense organs Visual Fields business Glaucoma Open-Angle 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-60355-1 |
| Popis: | Central visual field (CVF) loss is important in maintaining vision-related quality of life in eyes with open-angle glaucoma (OAG). The present study investigated whether nasalized location of central retinal vessel trunk (CRVT) at baseline is associated with rapid rate of CVF loss in early-stage OAG eyes. This study included 76 OAG eyes with high nasalization CRVT [HNL] group and 75 OAG eyes with low nasalization CRVT [LNL] group matched for glaucoma severity at baseline that showed progressive visual field (VF) loss. The rates of mean threshold changes at various regions were compared in the two groups using a linear mixed model. Clinical variables associated with rapid rate of CVF progression were also identified using a linear mixed model. The rate of CVF loss in the central 10° was significantly higher in the HNL group than that in the LNL group (−0.452 dB/year vs. −0.291 dB/year, P P P |
| Databáze: | OpenAIRE |
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