Accuracy of carboxyhemoglobin dilution method for the measurement of circulating blood volume
| Autor: | Satoshi Ohki, Yasuo Morishita, Noboru Oriuchi, Hideaki Obata, Fumio Kunimoto, Fumio Goto, Susumu Ishikawa, Yukitaka Isa, Tetsuya Koyano |
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| Rok vydání: | 2000 |
| Předmět: |
Male
Accuracy and precision Blood Volume business.industry Blood volume General Medicine Intensive care unit Standard deviation Chromium Radioisotopes law.invention Dilution chemistry.chemical_compound Anesthesiology and Pain Medicine chemistry Carboxyhemoglobin law Anesthesia Intensive care Cardiopulmonary bypass Medicine Humans Female Prospective Studies business |
| Zdroj: | Canadian journal of anaesthesia = Journal canadien d'anesthesie. 47(2) |
| ISSN: | 0832-610X |
| Popis: | Purpose: The management of circulating blood volume (BVc) is crucial in intensive care unit (ICU) patients. The purpose of this study was to verify the accuracy and precision of the carbon monoxide-labeled hemoglobin (CO-Hb) dilution method (CO method) by comparing it with the51Cr-labeled erythrocyte dilution method (51Cr method) for the measurement of BVc. Methods: A prospective study was performed in 18 patients who underwent coronary artery bypass grafting (CABG) under mild hypothermic cardiopulmonary bypass (CPB). The BVc was measured by both the CO method and the51Cr method at 24 hr after ICU admission in order to verify the accuracy and precision of the CO method. Paired data were assessed in absolute terms, and percentage errors were calculated by the degree of agreement. Results: Small mean differences and standard deviations between the CO method and the51Cr method (−70.2±184.8 mL) and small percentage errors (−0.49±1.29%) indicated the accuracy and precision of the CO method, and a close correlation was observed (r=0.97). Conclusion: The CO method can measure BVc with a similar degree of accuracy as the51Cr method. It is simple, repeatable and safe without the risk of exposure to radioactivity in the ICU. |
| Databáze: | OpenAIRE |
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