Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer. Part 2
Autor: | Raj G. Nair, Andrei Barasch, Marie Thérèse Genot, Judith A. E. M. Zecha, Judi N.A. van Diessen, Ron van der Brink, Liset Lansaat, Josep Arnabat-Domínguez, Mark M. Schubert, Lisette van der Molen, Irene Jacobi, Cesar A. Migliorati, Ludi E. Smeele, Michael R. Hamblin, Rene Jean Bensadoun, Joel B. Epstein, Judith E. Raber-Durlacher, Dan M.J. Milstein, Jan de Lange, Sharon Elad |
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Přispěvatelé: | MKA AMC (OII, ACTA), Orale Geneeskunde (OII, ACTA), Parodontologie (OII, ACTA), Maxillofacial Surgery (AMC), Oral Medicine, Periodontology |
Jazyk: | angličtina |
Rok vydání: | 2016 |
Předmět: |
Oncology
medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions medicine.medical_treatment chemical and pharmacologic phenomena Article 03 medical and health sciences 0302 clinical medicine Quality of life SDG 3 - Good Health and Well-being Clinical Protocols Internal medicine Mucositis Medicine Humans In patient Low-Level Light Therapy Low level laser therapy Chemotherapy business.industry Head and neck cancer fungi 030206 dentistry Chemoradiotherapy medicine.disease 3. Good health Surgery Radiation therapy Head and Neck Neoplasms 030220 oncology & carcinogenesis business |
Zdroj: | Supportive Care in Cancer, 24(6), 2793-2805. Springer Verlag Zecha, J A E M, Raber-Durlacher, J E, Nair, R G, Epstein, J B, Elad, S, Hamblin, M R, Barasch, A, Migliorati, C A, Milstein, D M J, Genot, M T, Lansaat, L, van der Brink, R, Arnabat-Dominguez, J, van Diessen, J, de Lange, J, Smeele, L E, Schubert, M M & Bensadoun, R J 2016, ' Low-level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer. Part 2 : proposed applications and treatment protocols ', Supportive Care in Cancer, vol. 24, no. 6, pp. 2793-2805 . https://doi.org/10.1007/s00520-016-3153-y |
ISSN: | 0941-4355 |
Popis: | Purpose There is a large body of evidence supporting the efficacy of low-level laser therapy (LLLT), more recently termed photobiomodulation (PBM) for the management of oral mucositis (OM) in patients undergoing radiotherapy for head and neck cancer (HNC). Recent advances in PBM technology, together with a better understanding of mechanisms involved and dosimetric parameters may lead to the management of a broader range of complications associated with HNC treatment. This could enhance patient adherence to cancer therapy, and improve quality of life and treatment outcomes. The mechanisms of action, dosimetric, and safety considerations for PBM have been reviewed in part 1. Part 2 discusses the head and neck treatment side effects for which PBM may prove to be effective. In addition, PBM parameters for each of these complications are suggested and future research directions are discussed. Methods Narrative review and presentation of PBM parameters are based on current evidence and expert opinion. Results PBM may have potential applications in the management of a broad range of side effects of (chemo)radiation therapy (CRT) in patients being treated for HNC. For OM management, optimal PBM parameters identified were as follows: wavelength, typically between 633 and 685 nm or 780–830 nm; energy density, laser or light-emitting diode (LED) output between 10 and 150 mW; dose, 2–3 J (J/cm2), and no more than 6 J/cm2 on the tissue surface treated; treatment schedule, two to three times a week up to daily; emission type, pulsed ( |
Databáze: | OpenAIRE |
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