Renal acid excretion contributes to acid-base regulation during hypercapnia in air-exposed swamp eel (Monopterus albus)
| Autor: | Do Thi Thanh Huong, Christian Damsgaard, Le Thi Hong Gam, Tobias Wang, Mark Bayley, Phan Vinh Thinh, Nguyen Thanh Phuong |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Physiology 030310 physiology Titratable acid Urine Aquatic Science Air-breathing fish Kidney 010603 evolutionary biology 01 natural sciences Excretion 03 medical and health sciences Animal science medicine Respiratory acidosis Molecular Biology Ecology Evolution Behavior and Systematics 0303 health sciences biology Chemistry Swamp eel medicine.disease biology.organism_classification medicine.anatomical_structure Insect Science Metabolic compensation Animal Science and Zoology medicine.symptom Renal compensation Arterial pH Hypercapnia Renal function |
| Zdroj: | Thinh, P V, Thanh Huong, D T, Gam, L T H, Damsgaard, C, Phuong, N T, Bayley, M & Wang, T 2019, ' Renal acid excretion contributes to acid-base regulation during hypercapnia in air-exposed swamp eel (Monopterus albus) ', The Journal of Experimental Biology, vol. 222 . https://doi.org/10.1242/jeb.198259 |
| DOI: | 10.1242/jeb.198259 |
| Popis: | The swamp eel (Monopterus albus) uses its buccal cavity to air breathe, while the gills are strongly reduced. It burrows into mud during the dry season, is highly tolerant of air exposure, and experiences severe hypoxia both in its natural habitat and in aquaculture. To study the ability of M. albus to compensate for respiratory acidosis, we implanted catheters to sample both arterial blood and urine during hypercapnia (4% CO2) in either water or air, or during whole-animal air exposure. These hypercapnic challenges caused an immediate reduction in arterial pH, followed by progressive compensation through a marked elevation of plasma HCO3− over the course of 72 h. There was no appreciable rise in urinary acid excretion in fish exposed to hypercapnia in water, although urine pH was reduced and ammonia excretion did increase. In the air-exposed fish, however, hypercapnia was attended by a large elevation of ammonia in the urine and a large rise in titratable acid excretion. The time course of the increased renal acid excretion overlapped with the time period required to elevate plasma HCO3−, and we estimate that the renal compensation contributed significantly to whole-body acid–base compensation. |
| Databáze: | OpenAIRE |
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