Adult form of Langerhans cell histiocytosis with pulmonary and hepatic Involvement mimicking malignancy in a patient with chronic hepatitis C infection
| Autor: | Andreas Christe, Adrian Thomas Huber, Martin H. Maurer, Barbara Moullet, Mirjam Kolev, Rupert Langer, Christoph Gräni, Nasser Semmo, Lukas Ebner, Verena Carola Obmann |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
Pathology medicine.medical_specialty lcsh:R895-920 Case Report 610 Medicine & health Malignancy 030218 nuclear medicine & medical imaging Myeloid Neoplasm 03 medical and health sciences 0302 clinical medicine Langerhans cell histiocytosis medicine Carcinoma Radiology Nuclear Medicine and imaging Lung business.industry Hepatocellular Hepatitis C medicine.disease medicine.anatomical_structure Liver Hepatocellular carcinoma Liver cirrhosis 570 Life sciences biology Differential diagnosis business 030217 neurology & neurosurgery |
| Zdroj: | Moullet, Barbara; Kolev, Mirjam; Ebner, Lukas; Langer, Rupert; Gräni, Christoph; Obmann, Verena; Maurer, Martin; Semmo, Nasser; Christe, Andreas; Huber, Adrian Thomas (2021). Adult form of Langerhans cell histiocytosis with pulmonary and hepatic Involvement mimicking malignancy in a patient with chronic hepatitis C infection. Radiology case reports, 16(2), pp. 327-333. Elsevier 10.1016/j.radcr.2020.11.022 Radiology Case Reports Radiology Case Reports, Vol 16, Iss 2, Pp 327-333 (2021) |
| Popis: | Langerhans cell histiocytosis (LCH) is a myeloid neoplasm with inflammatory properties. There are few published reports of adult LCH with liver involvement, which is still poorly understood, but shows high morbidity and mortality. We report a case of a 37-year-old woman suffering from hepatitis C showing a LCH affecting the lung as well as the liver. Consistent with histology, we found an early stage of a proliferative/granulomatous phase of hepatobiliary LCH, whereas pulmonary findings showed a nodular stage of adult pulmonary LCH. Although hepatocellular carcinoma is a common malignancy in patients suffering from hepatitis C, it is crucial to keep in mind differential diagnosis for newly appearing liver lesions. |
| Databáze: | OpenAIRE |
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