Video training and certification program improves reliability of postischemic neurologic deficit measurement in the rat
| Autor: | Miwa Izutsu, Rafael E Chaparro, Hideki Taninishi, Larry B. Goldstein, Molly Pearlstein, Huaxin Sheng, David S. Warner |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Certification education Video Recording Focal ischemia Severity of Illness Index 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Severity of illness Animals Humans Medicine Stroke Reliability (statistics) Neurologic Examination Observer Variation Video recording business.industry Behavioral neurology Teaching Infarction Middle Cerebral Artery Original Articles medicine.disease Rats 030104 developmental biology Neurology Physical therapy Neurology (clinical) Nervous System Diseases Cardiology and Cardiovascular Medicine business Observer variation 030217 neurology & neurosurgery |
| Zdroj: | Journal of Cerebral Blood Flow & Metabolism. 36:2203-2210 |
| ISSN: | 1559-7016 0271-678X |
| Popis: | Scoring systems are used to measure behavioral deficits in stroke research. Video-assisted training is used to standardize stroke-related neurologic deficit scoring in humans. We hypothesized that a video-assisted training and certification program can improve inter-rater reliability in assessing neurologic function after middle cerebral artery occlusion in rats. Three expert raters scored neurologic deficits in post-middle cerebral artery occlusion rats using three published systems having different complexity levels (3, 18, or 48 points). The system having the highest point estimate for the correlation between neurologic score and infarct size was selected to create a video-assisted training and certification program. Eight trainee raters completed the video-assisted training and certification program. Inter-rater agreement (κ score) and agreement with expert consensus scores were measured before and after video-assisted training and certification program completion. The 48-point system correlated best with infarct size. Video-assisted training and certification improved agreement with expert consensus scores (pretraining = 65 ± 10, posttraining = 87 ± 14, 112 possible scores, P 0.4 (pretraining = 4, posttraining = 9), and number of categories with an improvement in the κ score from pretraining to posttraining (n = 6). Video-assisted training and certification improved trainee inter-rater reliability and agreement with expert consensus behavioral scores in rats after middle cerebral artery occlusion. Video-assisted training and certification may be useful in multilaboratory preclinical studies. |
| Databáze: | OpenAIRE |
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