Acral melanocytic lesions in the United States: Prevalence, awareness, and dermoscopic patterns in skin-of-color and non-Hispanic white patients
| Autor: | Margaret I. Sanchez, Leyre Falto-Aizpurua, Harleen Arora, Sonal Choudhary, Kathryn J. Martires, David Polsky, James M. Grichnik, Priyanka Gumaste, Panta Rouhani Schaffer, Miguel Sanchez, Reshmi Madankumar, Aegean Chan, Shailee Patel, Jennifer A. Stein, Shadi Damanpour, Natalie Yin, Holly Kanavy, Penelope J. Kallis |
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| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Skin Neoplasms Dermoscopy Skin Pigmentation Dermatology Risk Assessment Acral lentiginous melanoma White People Cohort Studies 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Prevalence Humans Medicine Neoplasm Invasiveness Prospective Studies skin and connective tissue diseases Prospective cohort study Melanoma Aged Neoplasm Staging Aged 80 and over Observer Variation Nevus Pigmented integumentary system business.industry Biopsy Needle Awareness Middle Aged medicine.disease Immunohistochemistry United States 030220 oncology & carcinogenesis Cohort Florida Female Neoplasm staging business Observer variation Cohort study |
| Zdroj: | Journal of the American Academy of Dermatology. 74:724-730.e1 |
| ISSN: | 0190-9622 |
| DOI: | 10.1016/j.jaad.2015.11.035 |
| Popis: | Acral lentiginous melanoma has increased mortality compared with other melanoma subtypes and disproportionately affects ethnic minorities. Acral melanocytic lesions have not been well studied in diverse populations of the United States.We sought to assess the prevalence, awareness, and dermoscopic patterns of acral melanocytic lesions in skin-of-color and non-Hispanic white patients.We prospectively examined the palms and soles of 1052 patients presenting to dermatology clinics in New York, NY, and Miami, FL, from October 2013 to April 2015.Acral melanocytic lesions were observed in 36% of our cohort. Skin-of-color patients were more likely to have acral melanocytic lesions than non-Hispanic white patients (P .01). Acral melanocytic lesions correlated with increased mole counts, particularly on non-Hispanic white patients. The majority of lesions demonstrated benign dermoscopic patterns. We observed 2 lesions with the parallel ridge pattern in our cohort, both found to be atypical nevi on biopsy specimen. Patients often lacked awareness of the presence of their lesions.Interobserver variability in assessing dermoscopic patterns is a limitation.Melanocytic lesions of the palms and soles are common, particularly in a cohort of multiple ethnicities from the United States. Dermoscopy of acral lesions is an important clinical tool for diagnosis and management of these lesions. |
| Databáze: | OpenAIRE |
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