| Popis: |
With a view to ascertaining the frequency and severity of the various symptoms of serum reaction, five hundred patients receiving antitoxin serum were selected from the Louisa Minturn Hospital records. Consecutive cases were used, omitting only patients whose stay in the hospital was less than fourteen days, or whose complications masked the symptoms with which this paper is concerned. The antitoxin used was that dispensed by the New York Department of Health, so that the serum is somewhat modified. 1 Rash was taken as the determining factor in establishing reaction. It seems likely that there are cases which have no rash but give other symptoms, such as malaise, nausea, headache, pains in muscles, slight rise of temperature, etc. It is difficult to group these definitely. They come at the beginning of the second week of diphtheria when the patient begins to sit up out of bed and is |
