Impaired Endothelial Function in Patients with Myocardial Bridge
| Autor: | Sanem Nalbantgil, Uğur Önsel Türk, Azem Akilli, Filiz Özerkan, Cuneyt Turkoglu, Hamza Duygu, Mustafa Akin, Bahadır Kırılmaz, Mehdi Zoghi |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Myocardial bridge medicine.medical_specialty Brachial Artery Endothelium Coronary Vessel Anomalies Vasodilator Agents Administration Sublingual Myocardial Ischemia Isosorbide Dinitrate Coronary Angiography Severity of Illness Index Diagnosis Differential Coronary artery disease Internal medicine medicine.artery Intravascular ultrasound medicine Humans Radiology Nuclear Medicine and imaging Brachial artery Endothelial dysfunction Ultrasonography Interventional Retrospective Studies medicine.diagnostic_test business.industry Middle Aged Prognosis medicine.disease Vasodilation medicine.anatomical_structure Bridge (graph theory) Cardiology Female Endothelium Vascular Cardiology and Cardiovascular Medicine business Artery |
| Zdroj: | Echocardiography. 23:577-581 |
| ISSN: | 1540-8175 0742-2822 |
| DOI: | 10.1111/j.1540-8175.2006.00279.x |
| Popis: | OBJECTIVE The relationship between myocardial bridging (MB) and ischemic heart disease is still controversial. In this study, we aimed to evaluate the existing atherosclerosis and noninvasive endothelial function of brachial artery in patients with MB. METHODS The present study included 50 patients (group I) who had MB in left anterior descending (LAD) on coronary angiography. All of the coronary artery segments were evaluated by intravascular ultrasound (IVUS). Endothelial function was assessed with measurement of flow-mediated dilatation (FMD) and nitrate-dependent dilatation in the brachial artery. The study also included 30 healthy control subjects (group II). Patients in the group I were further subdivided into two subgroups based on the findings on IVUS: group IA included 20 patients without atherosclerotic lesions and group IB included 30 patients with atherosclerotic coronary artery disease in addition to MB. RESULTS FMD values were found to be significantly lower in the patients with MB (group I) than in the control (6.4 +/- 3% vs 11 +/- 4%, P |
| Databáze: | OpenAIRE |
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