Effects of staff education and standardizing dosing and collection times on vancomycin trough appropriateness in ward patients

Autor: Drayton A. Hammond, Taylor B. James, Jacob T. Painter, Katherine Lusardi, Lexis N. Atkinson
Jazyk: angličtina
Rok vydání: 2017
Předmět:
medicine.medical_specialty
Pharmaceutical Science
lcsh:RS1-441
Pharmacy
Staff education
Trough (economics)
mesh:Drug Monitoring
Pharmacists
030226 pharmacology & pharmacy
mesh:Quality Improvement
lcsh:Pharmacy and materia medica
Dose-Response Relationship
03 medical and health sciences
Plasma
0302 clinical medicine
mesh:Dose-Response Relationship
Vancomycin
Internal medicine
medicine
Pharmacokinetics
030212 general & internal medicine
Dosing
mesh:Pharmacists
mesh:Retrospective Studies
Morning
Original Research
Retrospective Studies
mesh:Drug
business.industry
Maintenance dose
Significant difference
lcsh:RM1-950
Retrospective cohort study
mesh:Vancomycin
Dose-Response Relationship Drug
Quality Improvement
mesh:Pharmacokinetics
United States
Surgery
mesh:Plasma
lcsh:Therapeutics. Pharmacology
mesh:United States
Drug Monitoring
Drug
business
medicine.drug
Zdroj: Pharmacy Practice (Granada), Volume: 15, Issue: 2, Article number: 949, Published: JUN 2017
Pharmacy Practice (Granada) v.15 n.2 2017
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud
instname
Pharmacy Practice, Vol 15, Iss 2, Pp 949-949 (2017)
Pharmacy Practice
Popis: Background: Many institutions have guidelines for initiation and monitoring, but not timing, of vancomycin. Objective: Our objective was to evaluate vancomycin trough collection appropriateness before and after an initiative to change the dosing and trough collection times in ward patients. Methods: A retrospective cohort study of ward patients from May 2014-16 who received scheduled intravenous vancomycin was performed. Nurse managers and pharmacists provided staff education. Differences between pre- and post-intervention groups were compared using student’s t-test for continuous data and chi-square test for categorical data. Results: Baseline characteristics were similar between the pre-intervention (n=124) and post-intervention (n=122) groups except for weight-based maintenance dose (15.3 mg/kg vs. 16.5 mg/kg, p=0.03) and percentage of troughs collected with morning labs (14% vs. 87%, p
Databáze: OpenAIRE