Assessment of structural and functional myocardial characteristics in patients with chronic coronary artery disease and various glycemic status

Autor: Mamedov Mn, M. A. Umetov, E. A. Poddubskaya, M. A. Kokozheva, B. U. Mardanov, V. A. Kutsenko
Jazyk: ruština
Rok vydání: 2021
Předmět:
Zdroj: Кардиоваскулярная терапия и профилактика, Vol 20, Iss 7 (2021)
ISSN: 2619-0125
1728-8800
Popis: Aim. To study the structural and functional myocardial characteristics in patients with exertional angina and type 2 diabetes in comparison with those without diabetes to identify combined hemodynamic changes.Material and methods. Patients were divided into two groups depen - ding on the glycemic status. The first group consisted of 49 patients (mean age, 57,9±1,04 years; male/female, 35/14) with coronary artery disease (CAD) and type 2 diabetes, while the second one (control) — 51 patients (60,2±0,9 years, 34/17) with CAD and without diabetes. Patients were surveyed using a standard questionnaire that included socio-demographic parameters, behavioral risk factors, clinical status, medications received, and comorbidities. Diagnostic investigations were carried out, including resting electrocardiography, transthoracic echocardiography and cycle ergometry.Results. Among patients with CAD and type 2 diabetes, hypertension occurred 20% more often compared with the control group — 98 vs 78% (pConclusion. The combination of chronic CAD and type 2 diabetes is cha - racterized by a more common combination with hypertension, impaired central and intracardiac hemodynamics, as well as left ventricular hypertrophy. In people with diabetes, impaired systolic and diastolic myocardial function is combined with reduced exercise tolerance.
Databáze: OpenAIRE