Pyrrole and indole alkaloids from an endophyticFusarium incarnatum(HKI00504) isolated from the mangrove plantAegiceras corniculatum

Autor:	Wenhan Lin, Kerstin Voigt, Zi-Wei Deng, Klaus-Dieter Menzel, Yi Ding, Isabel Sattler, Gundela Peschel, Ingrid Groth, Liya Li
Rok vydání:	2008
Předmět:	Fusarium Indoles Stereochemistry Pharmaceutical Science Fungus Endophyte Analytical Chemistry chemistry.chemical_compound Alkaloids Drug Discovery Pyrroles Primulaceae Pyrrole Pharmacology Indole test Molecular Structure biology Chemistry Organic Chemistry Fusarium incarnatum General Medicine Myrsinaceae biology.organism_classification Complementary and alternative medicine Molecular Medicine Aegiceras corniculatum
Zdroj:	Journal of Asian Natural Products Research. 10:765-770
ISSN:	1477-2213 1028-6020
DOI:	10.1080/10286020802031106
Popis:	Two new pyrrole alkaloids, N-[4-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-butyl]-acetamide (1) and N-[5-(2-formyl-5-hydroxymethyl-pyrrol-1-yl)-pentyl]-acetamide (2), and a new indole derivative (3aR,8aR)-3a-acetoxyl-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indol (3) were isolated, together with ( - )-3a-hydroxyfuroindoline, (3aR,8aS)-1-acetyl-1,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indol-3a-ol, and N-acetyltryptamine A, from an endophytic ascomycetous fungus, Fusarium incarnatum (HKI00504), which was isolated from the mangrove plant Aegiceras corniculatum. The structures of compounds 1-3 were determined on the basis of extensive spectroscopic data analyses.
Databáze:	OpenAIRE
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