Innate and adaptive immunity of periodontal disease. From etiology to alveolar bone loss
| Autor: | Celia Guerrero-Velázquez, Fernando Martínez-Esquivias, Juan Manuel Guzmán-Flores, Julieta Saraí Becerra-Ruiz, Luz Andrea Martínez-Pérez |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Periodontium
Alveolar Bone Loss Inflammation Disease 03 medical and health sciences 0302 clinical medicine Immune system Immunity medicine Humans Periodontitis General Dentistry Dental alveolus Periodontal Diseases business.industry 030206 dentistry medicine.disease Acquired immune system Immunity Innate Otorhinolaryngology 030220 oncology & carcinogenesis Immunology medicine.symptom business Homeostasis |
| Zdroj: | Oral diseasesREFERENCES. 28(6) |
| ISSN: | 1601-0825 |
| Popis: | Periodontal disease refers to inflammation of the tissues that support the tooth. It is of multifactorial etiology. Innate and adaptive immune cells participate jointly through the release of their molecules and mechanisms of action in order to maintain homeostasis in periodontal tissues, so the host's immune response plays an essential role in defense against microorganisms. However, bacterial persistence and the dysregulation of the immune system as an exaggerated response can lead to the worsening of periodontal disease, leading to loss of gingival tissue and alveolar bone and thereby loss of teeth. Therefore, a better understanding of the cellular mechanisms involved in the development of periodontal disease is necessary to design new treatments and prophylactic measures in order to decrease the prevalence of this disease that afflicts a large part of the world population. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text