Multinational Prospective Cohort Study of Mortality Risk Factors in 198 ICUs of 12 Latin American Countries over 24 Years: The Effects of Healthcare-Associated Infections

Autor: Victor Daniel Rosenthal, Ruijie Yin, Sandra Liliana Valderrama-Beltran, Sandra Milena Gualtero, Claudia Yaneth Linares, Guadalupe Aguirre-Avalos, Julio Cesar Mijangos-Méndez, Miguel Ángel Ibarra-Estrada, Luisa Fernanda Jimenez-Alvarez, Lidia Patricia Reyes, Carlos Arturo Alvarez-Moreno, Maria Adelia Zuniga-Chavarria, Ana Marcela Quesada-Mora, Katherine Gomez, Johana Alarcon, Jose Millan Oñate, Daisy Aguilar-De-Moros, Elizabeth Castaño-Guerra, Judith Córdoba, Alejandro Sassoe-Gonzalez, Claudia Marisol Millán-Castillo, Lissette Leyva Xotlanihua, Lina Alejandra Aguilar-Moreno, Juan Sebastian Bravo Ojeda, Ivan Felipe Gutierrez Tobar, Mary Cruz Aleman-Bocanegra, Clara Veronica Echazarreta-Martínez, Belinda Mireya Flores-Sánchez, Yuliana Andrea Cano-Medina, Edwin Giovannny Chapeta-Parada, Rafael Antonio Gonzalez-Niño, Maria Isabel Villegas-Mota, Mildred Montoya-Malváez, Miguel Ángel Cortés-Vázquez, Eduardo Alexandrino Medeiros, Dayana Fram, Daniela Vieira-Escudero, Zhilin Jin
Rok vydání: 2022
Předmět:
Zdroj: Journal of Epidemiology and Global Health. 12:504-515
ISSN: 2210-6014
DOI: 10.1007/s44197-022-00069-x
Popis: Background The International Nosocomial Infection Control Consortium (INICC) has found a high ICU mortality rate in Latin America. Methods A prospective cohort study in 198 ICUs of 96 hospitals in 46 cities in 12 Latin American countries to identify mortality risk factors (RF), and data were analyzed using multiple logistic regression. Results Between 07/01/1998 and 02/12/2022, 71,685 patients, followed during 652,167 patient-days, acquired 4700 HAIs, and 10,890 died. We prospectively collected data of 16 variables. Following 11 independent mortality RFs were identified in multiple logistic regression: ventilator-associated pneumonia (VAP) acquisition (adjusted odds ratio [aOR] = 1.17; 95% CI: 1.06–1.30; p p p p p p p p p p p p p Conclusion Some of the identified mortality RFs are unlikely to change, such as the income level of the country, facility ownership, hospitalization type, ICU type, and age. But some of the mortality RFs we found can be changed, and efforts should be made to reduce CL-days, UC-days, MV-utilization ratio, UC-utilization ratio, and lower VAPs and CAUTI rates.
Databáze: OpenAIRE