Maclura tinctoria Extracts: In Vitro Antibacterial Activity against Aeromonas hydrophila and Sedative Effect in Rhamdia quelen
| Autor: | Guerino Bandeira Junior, Luísa Barichello Barbosa, Amanda Leitão Gindri, Bibiana Petri da Silveira, Bernardo Baldisserotto, Quelen Iane Garlet, Luana da Costa Pires, Patrícia Rodrigues, Agueda Castagna de Vargas, Rodrigo Coldebella, Berta Maria Heinzmann, Cristiane Pedrazzi, Lenise de Lima Silva |
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| Rok vydání: | 2021 |
| Předmět: |
Aeromonas hydrophila
QH301-705.5 QH426-470 Aquatic Science medicine.disease_cause antimicrobials 03 medical and health sciences Genetics medicine Biology (General) Ecology Evolution Behavior and Systematics fish culture 030304 developmental biology 0303 health sciences silver catfish Ecology biology Traditional medicine 030306 microbiology Chemistry Pathogenic bacteria Maclura tinctoria biology.organism_classification Antimicrobial sedation Aeromonas Polyphenol visual_art visual_art.visual_art_medium Bark Antibacterial activity |
| Zdroj: | Fishes, Vol 6, Iss 25, p 25 (2021) Fishes Volume 6 Issue 3 |
| ISSN: | 2410-3888 |
| DOI: | 10.3390/fishes6030025 |
| Popis: | Maclura tinctoria is a tree species native from Brazil and rich in phenolic compounds. Since plant antibacterial activity is highly associated with phenolic compound concentration, we aim to evaluate the in vitro antimicrobial activity of different extracts against fish pathogenic bacteria. In addition, some phenolic compounds have central depressant effects and can be useful in aquaculture due to possible sedative and/or anesthetic effects. Four M. tinctoria extracts were extracted separately with ethanol leaves (LE), bark (BE), heartwood (HE), and the sapwood (SE). In vitro antimicrobial activity was tested against Aeromonas strains at concentrations of 6400 to 3.125 μg/mL. The sedative effect was evaluated for 24 h with 30 and 100 mg/L concentrations. Chemical composition was analyzed by HPLC-DAD-MS. The HE extract had the best MIC (400 µg/mL) and MBC (800 µg/mL) compared to the LE, BE, and SE extracts. LE extract induced deep sedation and the BE, SE, and HE extracts induced light sedation. Additionally, BE, SE, and HE induced a normal behavior without side effects. Polyphenolic compounds with antimicrobial activity and sedative effects were identified mainly in HE. Thus, HE extract is safe and can be used as a sedative for silver catfish. |
| Databáze: | OpenAIRE |
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