An arginine vasotocin-like neuropeptide is present in the nervous system of the marine mollusc Aplysia californica

Autor: G.J. Moore, Karl Lederis, V. Gill, J.A. Thornhill, Ken Lukowiak
Rok vydání: 1981
Předmět:
Zdroj: Brain Research. 206:213-218
ISSN: 0006-8993
DOI: 10.1016/0006-8993(81)90119-0
Popis: Radioimmunoassays and high pressure liquid chromotography have been used to demonstrate the presence of an arginine-vasotocin-like peptide (AVT) in the anterior ganglia of Aplysia. Previously, AVT, using similar methods, was found to be present only in vertebrates. AVT when perfused over the abdominal ganglion (10 −6 –10 −12 M) was found to increase the bursting activity of R 15 , to decrease the bursting activity of L 3 –L 6 and to increase the CNS's suppressive influence over the gill withdrawal reflex evoked by siphon stimulation. The AVT present in the nervous system of Aplysia may mediate long-term suppression of gill reflex behaviors induced by factors such as satiation and, as well, regulate the activity of certain neurosecretory neurons.
Databáze: OpenAIRE