Bone response to a novel highly porous surface in a canine implantable chamber
| Autor: | Fred Dimaano, Tian Hua, Kazuho Iesaka, William L. Jaffe, Sally R. Frenkel |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Chromium
Materials science Surface Properties Biomedical Engineering chemistry.chemical_element Biomaterials Dogs Coated Materials Biocompatible Implants Experimental Ultimate tensile strength Alloys Animals Femur Porosity Fixation (histology) Titanium Bone Development Biomechanics Cobalt-chrome Cobalt Penetration (firestop) Radiography Durapatite chemistry Microscopy Electron Scanning Diffusion Chambers Culture Stress Mechanical Implant Biomedical engineering |
| Zdroj: | Journal of Biomedical Materials Research. :387-391 |
| ISSN: | 1097-4636 0021-9304 |
| DOI: | 10.1002/jbm.b.30104 |
| Popis: | Long-term survival of uncemented hip components is dependent upon successful biological fixation. This study examined a new prosthetic surface treatment consisting of a highly porous open structure of commercially pure titanium, Tritanium Dimensionalized Metal; its overall porosity is approximately 65-70%. With the use of an implantable chamber in dogs, the effects of this treatment on bone ingrowth and strength of attachment were compared to both titanium (overall porosity of 30-35%) and cobalt chrome beads (overall porosity of 35-40%), with and without hydroxyapatite coating. At 6 and 12 weeks, chambers were explanted and specimens underwent high-resolution radiographic imaging and mechanical testing. At 12 weeks, Tritanium surfaces had greater bone penetration and tensile strength than remaining surface types. Over 40% of the Tritanium specimens had a tensile strength greater than 500 N, exceeding the testing capability of the servohydraulic equipment. The highly porous Tritanium surfaces allow for a far greater amount of bone ingrowth than beaded surfaces, and may create a geometry that enhances mechanical strength. Tritanium Dimensionalized Metal surface treatment may result in a clinically valuable implant fixation surface to induce rapid ingrowth and a strong bone-implant interface, contributing to increased implant survivorship. |
| Databáze: | OpenAIRE |
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