Comparison of nitrazepam with triazolam in insomniac outpatients
| Autor: | L. Lundin, L. E. Dahl, S. J. Dencker, H. Kullingsjö |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Male Triazolam Time Factors Nitrazepam medicine.drug_class Double blind Hypnotic Drug treatment Double-Blind Method Sleep Initiation and Maintenance Disorders medicine Humans Aged Clinical Trials as Topic business.industry Middle Aged Nitrazepam 5 MG Psychiatry and Mental health Anti-Anxiety Agents Anesthesia Female business medicine.drug |
| Zdroj: | Acta psychiatrica Scandinavica. 65(2) |
| ISSN: | 0001-690X |
| Popis: | The short-acting hypnotic, triazolam 0.5 mg, was compared in a 7-day double-blind study with the longer acting drug, nitrazepam 5 mg. Of the 60 patients enrolled, 29 in each drug treatment group completed the study and were evaluated. All significant differences found favoured triazolam. On the first night, triazolam was found to be significantly more effective than nitrazepam in inducing and maintaining sleep and in increasing its overall duration. The patients' subjective preference, reflecting the depth of sleep experienced and the effect of the medication, reached highly significant levels in favour of triazolam. Later in the study the differences between the drugs disappeared although the depth of sleep as judged in the study was better with triazolam. |
| Databáze: | OpenAIRE |
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