Correlation of hematological parameters and cycle threshold in ambulatory patients with SARS‐CoV‐2 infection

Autor: C.E. Covantes-Rosales, D A Girón-Pérez, Ulises Mercado-Salgado, Rocío Alejandra Ruiz-Manzano, K.J.G. Díaz-Resendiz, G.A. Toledo-Ibarra, Manuel Iván Girón-Pérez, Ansonny Jhovany Ojeda-Durán, G.H. Ventura-Ramón, A.B. Benitez-Trinidad
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Laboratory Hematology
ISSN: 1751-553X
1751-5521
Popis: Introduction Former studies have shown that hematologic parameters are affected by the SARS‐CoV‐2 infection which has caused a global health problem. Therefore, this research aims to identify the most frequent symptoms and comorbidities in SARS‐CoV‐2 infected outpatients; besides, to analyze hematological parameters and their correlation with cycle threshold (Ct) values. Methods We analyzed a total of sixty outpatients with SARS‐CoV‐2 infection. They were divided according to sex. Afterward, a questionnaire was carried out to find out their symptoms and comorbidities. Additionally, blood biometry data were correlated with the Ct value, respectively. Results Sixty patients were analyzed; the mean age was 43 years. All patients were from Nayarit, Mexico. The frequency index showed that the main symptoms were headache and anosmia, and the comorbidities were obesity and smoking. The analysis of blood biometry showed a clear increase in red blood cells (RBC) related parameters in women. In both sexes an increase in the number of white blood cells (WBC) was observed. Also, all the hematological alterations correlated with the grade of infection. Conclusion Headache and anosmia are the most common symptoms according to the frequency index, the main comorbidities were obesity and smoking. Also, there is a Ct value correlation with hematological parameters (WBC, mean corpuscular volume, mean corpuscular hemoglobin, hemoglobin); they can be used as a prognostic marker of infection.
Databáze: OpenAIRE
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