Cell kinetics and hormonal features in relation to pathological stage in breast cancer

Autor: Nadia Lundi, Chiara Bonaguri, Ariele Saragoni, Patrizia Gentilini, Dino Amadori, Enrico Magni, Antonio Vio, Oriana Nanni, Wainer Zoli, Angela Riccobon
Rok vydání: 1991
Předmět:
Zdroj: Breast Cancer Research and Treatment. 18:19-25
ISSN: 1573-7217
0167-6806
Popis: Proliferative activity (expressed as 3H-thymidine labeling index, 3H-TdR LI) was evaluated on a series of 281 primary tumors recruited in two years in 6 different institutions from central Italy. 3H-TdR LI proved to be low in intraductal, or well and moderately differentiated, or hormone receptor positive tumors. Conversely, no relation was observed between 3H-TdR LI and menopause, tumor size, or lymph node involvement. An inverse relation was observed between 3H-TdR LI and hormone receptor content. Specific patterns of 3H-TdR LI value and ER content association were observed as a function of menopause, lymph nodal status, and degree of lymph nodal involvement.
Databáze: OpenAIRE