Cell kinetics and hormonal features in relation to pathological stage in breast cancer
| Autor: | Nadia Lundi, Chiara Bonaguri, Ariele Saragoni, Patrizia Gentilini, Dino Amadori, Enrico Magni, Antonio Vio, Oriana Nanni, Wainer Zoli, Angela Riccobon |
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| Rok vydání: | 1991 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.drug_class Mammary gland Estrogen receptor Breast Neoplasms Biology Breast cancer Internal medicine medicine Humans Lymph node Neoplasm Staging medicine.disease Menopause medicine.anatomical_structure Endocrinology Receptors Estrogen Oncology Estrogen Hormone receptor Cancer research Female Lymph Receptors Progesterone Cell Division |
| Zdroj: | Breast Cancer Research and Treatment. 18:19-25 |
| ISSN: | 1573-7217 0167-6806 |
| Popis: | Proliferative activity (expressed as 3H-thymidine labeling index, 3H-TdR LI) was evaluated on a series of 281 primary tumors recruited in two years in 6 different institutions from central Italy. 3H-TdR LI proved to be low in intraductal, or well and moderately differentiated, or hormone receptor positive tumors. Conversely, no relation was observed between 3H-TdR LI and menopause, tumor size, or lymph node involvement. An inverse relation was observed between 3H-TdR LI and hormone receptor content. Specific patterns of 3H-TdR LI value and ER content association were observed as a function of menopause, lymph nodal status, and degree of lymph nodal involvement. |
| Databáze: | OpenAIRE |
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