Increased coronary intervention rate among diabetic patients with poor glycaemic control: A cross-sectional study
| Autor: | Yüksel Peker, Mehmet Akif Ozturk, Süha Çetin, Nadir Barındık, Ersin İmren |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Blood Glucose
Male medicine.medical_specialty endocrine system diseases Cross-sectional study medicine.medical_treatment Coronary Angiography Revascularization Logistic regression Body Mass Index Diabetes mellitus Internal medicine Odds Ratio Humans Hypoglycemic Agents Medicine Aged Retrospective Studies Glycated Hemoglobin lcsh:R5-920 business.industry Type 2 Diabetes Mellitus nutritional and metabolic diseases Odds ratio Middle Aged medicine.disease Confidence interval Cross-Sectional Studies glycaemic control Diabetes Mellitus Type 2 Cardiology Regression Analysis Female revascularization business lcsh:Medicine (General) Body mass index coronary artery disease Research Article |
| Zdroj: | Bosnian Journal of Basic Medical Sciences, Vol 14, Iss 1 (2014) |
| Popis: | The relationship between glycaemic control and coronary artery disease (CAD) in type 2 diabetes mellitus (T2DM) is controversial. In the current cross-sectional study, we addressed the relationship between Hemoglobin A1c (HbAlc) values and the need for revascularization among diabetic patients undergoing coronary angiography. A total of 301 consecutive patients with known T2DM (age 61.8 +/- 10.1 years, 46.2 % women) requiring coronary angiography due to CAD symptoms were included. T2DM patients were categorized into two groups based on their HbAlc values: 93 (30.9%) diabetics with good glycaemid control (HbA1c 7 %). A total of 123 patients (40.9%) required revascularization. The revascularization rate was 28.0% among T2DM patients with good glycaemic control and 46.6% among T2DM patients with poor glycaemic control, respectively (p=0.002). In a logistic regression analysis, the need for revascularization was predicted by poor glycaemic control (Odds Ratio [OR] 2.26, 95% Confidence Interval [Cl] 1.32-3.82; p=0.003) adjusted for age, gender, Body-Mass-Index and diabetes duration. Moreover, there was a linear relationship between HbA1c values and number of affected coronary arteries (r= 0.169;p=0.003). Our data suggest that there is a close association between poor glycaemic control and increased revascularization rate in T2DM, which should be considered in primary and secondary prevention models. (c) 2014 Association of Basic Medical Sciences of FB&H. All rights reserved |
| Databáze: | OpenAIRE |
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