Clinical Features and Prognosis of Herpetic Anterior Uveitis
| Autor: | Cihan Ünlü, Tuğba Aydoğan Gezginaslan, Esra Kardes, Ahmet Bahadir Ergin, Betul Ilkay Sezgin Akcay, Kansu Tahir Bozkurt |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Visual acuity genetic structures herpetic anterior uveitis Visual impairment Iris atrophy lcsh:Medicine 03 medical and health sciences Elevated intraocular pressure 0302 clinical medicine lcsh:Ophthalmology Cornea Ophthalmology medicine business.industry Medical record lcsh:R medicine.disease granulomatous keratic precipitates eye diseases Surgery medicine.anatomical_structure lcsh:RE1-994 030221 ophthalmology & optometry Original Article sense organs Anterior uveitis medicine.symptom business iris atrophy 030217 neurology & neurosurgery Uveitis oral acyclovir |
| Zdroj: | Türk Oftalmoloji Dergisi, Vol 46, Iss 3, Pp 109-113 (2016) Turkish Journal of Ophthalmology |
| ISSN: | 1300-0659 |
| DOI: | 10.4274/tjo.92053 |
| Popis: | Objective To evaluate clinical features, complications, visual outcomes and treatment modalities in patients clinically diagnosed with herpetic anterior uveitis (AU). Materials and methods We retrospectively reviewed the medical records of 67 patients seen at the Umraniye Training and Research Hospital, Ophthalmology Clinic, Uveitis and Cornea Department from January 2009 to June 2013. Results Thirty-seven patients (55.2%) were female and 30 (44.7%) patients were male. The average follow-up period was 12.9 ± 10.6 months (range: 1-45 months). The most common ocular findings were granulomatous keratic precipitates (KPs) (82.2%), corneal involvement (62.6%), iris atrophy (41.7%) and transient elevated intraocular pressure (IOP) (40.2%). Recurrences were observed in 46.2% of the eyes and the median recurrence rate was 1.0 during the follow-up period. Topical steroids and oral antiviral (acyclovir) therapy were applied to all patients during active episodes. Long-term oral acyclovir was used in 29.8% of the patients. Recurrence rates were significantly lower in patients who used oral acyclovir for more than 6 months, whereas complications rates and final visual acuity did not show any difference between groups. Final visual acuity was better than 20/40 in 61.1% of eyes, and visual impairment was due to corneal scarring or cataract formation. Conclusion Herpetic AU can present with or without corneal involvement. Granulomatous KPs, iris atrophy and elevated IOP are important clinical findings for the diagnosis of cases without corneal involvement. Long-term oral acyclovir treatment (more than 6 months) and is important to decrease recurrence rates and possible complications. Visual prognosis is favorable in cases without corneal scarring. |
| Databáze: | OpenAIRE |
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