Facile synthesis of Silver nanoparticles with medicinal grass and its biological assessment
Autor: | Murugesan Muthalagu, Saranya Kannan, Manisha Vidyavathy S, Satheeshkumar Balu, Swetha Andra |
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Rok vydání: | 2019 |
Předmět: |
inorganic chemicals
Green chemistry Materials science 02 engineering and technology 010402 general chemistry 01 natural sciences Silver nanoparticle Ultraviolet visible spectroscopy medicine General Materials Science Fourier transform infrared spectroscopy Cytotoxicity health care economics and organizations chemistry.chemical_classification biology Mechanical Engineering Biomolecule Saccharum spontaneum technology industry and agriculture 021001 nanoscience & nanotechnology Condensed Matter Physics medicine.disease biology.organism_classification Hemolysis 0104 chemical sciences chemistry Mechanics of Materials Nanomedicine 0210 nano-technology Antibacterial activity Nuclear chemistry |
DOI: | 10.3762/bxiv.2019.58.v1 |
Popis: | Biogenic synthesis of silver nanoparticles (SS-Ag NPs) using the extract of Saccharum spontaneum (SS) via green chemistry route was investigated for their in-vitro cytotoxicity on osteoblast-like cells and bactericidal effect. Synthesized SS-Ag NPs were analyzed using TEM, FTIR, XRD and UV Vis spectroscopy techniques. The biomolecules present in S. spontaneum were responsible for the reduction and capping of silver nanoparticles. A heterogenous mixture of SS-Ag NPs which consists of triangle, hexagonal, spherical and rod-like structures was obtained. Furthermore, the synthesized SS-Ag NPs were tested for in a broad spectrum of antibacterial activity against E. coli, S. aureus, K. pneumonia and P. aeruginosa and it showed significant inhibitory effect. For the first time, the enhancement in the proliferation rate of MG63 cells with SS-Ag NPs is reported. |
Databáze: | OpenAIRE |
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