Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage
| Autor: | Craig Anderson, Raf Brouns, Joseph Kwan, David Werring, John Chalmers, Emma Heeley, Graeme Hankey, Pablo Lavados, Hauke Schneider, Dominique Hervé, Serge Timsit, Richard Lindley, Elsa Azevedo, Francesco Corea, Tiago Gregorio, Daniel Strbian, Filip Scheperjans, Emmanuel Touzé, Seye Abimbola, Sylvie De Raedt, Mark Woodward, Andrea Zini, Bruce Neal, Jacques De Keyser, Sami Curtze, C.J.M. Klijn, María del Mar Castellanos, Charlotte Cordonnier, Thompson Robinson, Danilo Toni, Laurent Billot, Candice Delcourt, Christian Stapf, Tissa Wijeratne, Victoria Haunton |
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| Přispěvatelé: | Neurology, Clinical sciences, Neuroprotection & Neuromodulation, The Georges Institute for International Health, The University of Sydney, Neurology Department (RPA Hospital - Neurology), Royal Prince Alfred Hospital, Department of Neurology, Xuanwu Hospital of Capital-University of Medical Sciences / Beijing, Centre for Epidemiological Studies and Clinical Trials, Shanghai Jiao Tong University School of Medicine-Ruijin Hospital, Deparment of Neurology (LARIBOISIERE - Neurologie), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Neurology Department (RPH Hospital - Neurology), Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, University of Leicester, Servicio de Neurologia (SANTIAGO - Neurologie), Universidad del Desarrollo, Department of Neurology (JH Hospital - Neurology), University of Newcastle [Australia] (UoN), Department of Neurology (BOATOU - Neurology), Boatou Central Hospital, Department of Neurology (TANGSHAN - Neurology), Yutian County Hospital, National Health and Medical Research Council Clinical Trials Centre, Melbourne Brain Centre (Melbourne Brain Centre), University of Melbourne |
| Rok vydání: | 2013 |
| Předmět: |
MESH: Cerebral Hemorrhage
Male Time Factors [SDV]Life Sciences [q-bio] Blood Pressure 030204 cardiovascular system & hematology MESH: Hypertension law.invention Disability Evaluation 0302 clinical medicine Randomized controlled trial law Modified Rankin Scale Single-Blind Method Stroke MESH: Aged MESH: Middle Aged MESH: Disability Evaluation MESH: Blood Pressure General Medicine Middle Aged 3. Good health Anesthesia Acute Disease Hypertension MESH: Acute Disease Female medicine.medical_specialty 610 Medicine & health 03 medical and health sciences Hypertension/complications medicine Humans In patient Adverse effect Antihypertensive Agents Aged Cerebral Hemorrhage Intracerebral hemorrhage MESH: Antihypertensive Agents MESH: Humans business.industry MESH: Time Factors Odds ratio MESH: Single-Blind Method medicine.disease Cerebral Hemorrhage/complications MESH: Male Confidence interval Surgery Blood pressure Blood pressure lowering Antihypertensive Agents/administration & dosage business MESH: Female 030217 neurology & neurosurgery |
| Zdroj: | Anderson, Craig S.; Heeley, Emma; Huang, Yining; Wang, Jiguang; Stapf, Christian; Delcourt, Candice; Lindley, Richard; Robinson, Thompson; Lavados, Pablo; Neal, Bruce; Hata, Jun; Arima, Hisatomi; Parsons, Mark; Li, Yuechun; Wang, Jinchao; Heritier, Stephane; Li, Qiang; Woodward, Mark; Simes, R. John; Davis, Stephen M.; ... (2013). Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage. New England journal of medicine NEJM, 368(25), pp. 2355-2365. Massachusetts Medical Society MMS 10.1056/NEJMoa1214609 New England Journal of Medicine New England Journal of Medicine, Massachusetts Medical Society, 2013, 368 (25), pp.2355-65. ⟨10.1056/NEJMoa1214609⟩ |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/NEJMoa1214609 |
| Popis: | International audience; BACKGROUND: Whether rapid lowering of elevated blood pressure would improve the outcome in patients with intracerebral hemorrhage is not known. METHODS: We randomly assigned 2839 patients who had had a spontaneous intracerebral hemorrhage within the previous 6 hours and who had elevated systolic blood pressure to receive intensive treatment to lower their blood pressure (with a target systolic level of |
| Databáze: | OpenAIRE |
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