Hyperprolactinaemia and Pituitary Adenomas in Adolescence
| Autor: | P Dissaneevate, G L Warne |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Adenoma
Male endocrine system medicine.medical_specialty Cabergoline Adolescent Endocrinology Diabetes and Metabolism Physiology Pituitary neoplasm Serum prolactin Elevated serum Endocrinology Pituitary adenoma Internal medicine Humans Medicine Pituitary Neoplasms Ergolines Bromocriptine business.industry Hyperprolactinaemia medicine.disease Hyperprolactinemia Dopamine Agonists Pediatrics Perinatology and Child Health Female business hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Journal of Pediatric Endocrinology and Metabolism. 11 |
| ISSN: | 2191-0251 0334-018X |
| DOI: | 10.1515/jpem.1998.11.4.531 |
| Popis: | Six adolescents, five males with prolactin-secreting pituitary macroadenomas and one female with idiopathic hyperprolactinaemia, are described. Their ages at presentation ranged from 13 years 7 months to 16 years 6 months. Presenting symptoms included headache, visual field defect, arrested growth and puberty. Only two cases had galactorrhoea. Every case had an elevated serum prolactin level. Three had surgery before the results of serum prolactin were to hand. Each patient was treated with bromocriptine. Bromocriptine suppressed serum prolactin level to normal in four cases, but in the girl with idiopathic hyperprolactinaemia, bromocriptine was not useful. In two boys, serum prolactin was not suppressed with bromocriptine therapy alone, and they were subsequently treated with cabergoline, surgery and irradiation. Nevertheless, in children and adolescents with prolactin-secreting pituitary adenoma, bromocriptine should be the first line of treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|