Attention-Deficit/Hyperactivity Disorder Diagnosis, Co-Morbidities, Treatment Patterns, and Quality of Life in a Pediatric Population in Central and Eastern Europe and Asia
| Autor: | Ján Šuba, Mária Palaczky, Salih Zoroglu, Richard Walton, Tong Xu, Mircea Tiberiu, Petra Uhlíková, Kenneth D. Gadow, Gavan Harrison, Ferenc Martenyi, Sungdo David Hong, Tamas Treuer, Susan Shur-Fen Gau |
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| Rok vydání: | 2009 |
| Předmět: |
Cross-Cultural Comparison
Male Pediatrics medicine.medical_specialty Asia Adolescent Comorbidity Cohort Studies Pharmacotherapy Population Groups Quality of life mental disorders medicine Humans Attention deficit hyperactivity disorder Pharmacology (medical) Europe Eastern Prospective Studies Child business.industry medicine.disease Checklist Europe Psychiatry and Mental health Treatment Outcome Attention Deficit Disorder with Hyperactivity Pediatrics Perinatology and Child Health Quality of Life Attention deficit Female Co morbidity Observational study business Pediatric population |
| Zdroj: | Journal of Child and Adolescent Psychopharmacology. 19:363-376 |
| ISSN: | 1557-8992 1044-5463 |
| Popis: | Attention deficit/hyperactivity disorder (ADHD) is often poorly understood, and treatment practices are variable. This 12-month, prospective, observational study provides information about the diagnosis, co-morbidities, treatment patterns, and quality of life (QOL) of patients aged 6-17 years with ADHD symptoms from eastern Asia and central and eastern Europe. Here, we present baseline data for the 1068 enrolled and eligible patients in the study (median age 8 years, 82.2% male). Patients were grouped into two cohorts based on whether they were prescribed psycho- and/or pharmacotherapy (n = 794) or not (n = 274) at study entry. On average, patients receiving treatment were significantly older (9.1 vs. 8.4 years, p0.001), more severely ill (Clinical Global Impressions [CGI]-ADHD-S, 4.6 vs. 4.2, p0.001; Child Symptom Inventory-4 Parent Checklist (CSI-4) ADHD:C, 35.2 vs. 31.9, p0.001), and had significantly higher CSI-4 symptom severity scores relating to various co-morbidities than patients not receiving treatment. At study initiation, patient's health-related QOL was significantly impaired as measured on the Child Health and Illness Profile-Child Edition (CHIP-CE) rating scale, with significantly more impairment in the treated group of patients for the Comfort, Risks Avoidance, and Achievement domains. These results provide a description of ADHD and treatment practices in these regions and establish a baseline for gauging changes over time in the study sample. |
| Databáze: | OpenAIRE |
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