Positional distribution of fatty acids in rabbit lung phospholipids and triacylglycerols and effect of prolonged hyperoxy
| Autor: | Kamen Koumanov, Tania Neicheva, Georgi Nikolov Georgiev, Georgi Dimitrov |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Biophysics
chemistry.chemical_element Fraction (chemistry) Biochemistry Oxygen Palmitic acid Structure-Activity Relationship chemistry.chemical_compound Endocrinology Phosphatidylcholine Animals Lung Phospholipids Triglycerides chemistry.chemical_classification Phosphatidylethanolamine Chromatography Phosphatidylethanolamines Fatty Acids Fatty acid Oleic acid Membrane chemistry Phosphatidylcholines Rabbits |
| Zdroj: | Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 450:1-7 |
| ISSN: | 0005-2760 |
| DOI: | 10.1016/0005-2760(76)90293-9 |
| Popis: | Investigations have been carried out for the determination of the effect of high oxygen concentration in inspired gas mixture on the positional distribution of fatty acids in rabbit lung phospholipids and triacylglycerols. The following results were obtained: 1. 1. In the phosphatidylcholine fraction, the high oxygen concentration caused a quantitative increase of palmitic acid (16 : 0) at the α-position, and of myristic (14 : 0), heptadecenic (17 : 1) and arachidonic (20 : 4) acids at the β-position. 2. 2. In the phosphatidylethanolamine fraction, the high oxygen concentration caused an increase of oleic acid (18 : 1) at the α-position, and of palmitoleic (16 : 1) and heptadecenic (17 : 1) acids at the β-position. 3. 3. In the triacylglycerol fraction such changes were not observed. In connection with these effects of oxygen, its possible influence on membrane structures in the lung has been discussed. |
| Databáze: | OpenAIRE |
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