Primary hyperparathyroidism and hyperaminoaciduria
| Autor: | C.E. Dent, D.C. Cusworth, C.R. Scriver |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
medicine.medical_specialty
Hypercalcaemia Bone disease Clinical Biochemistry Osteitis Fibrosa Cystica Parathyroid hormone Biochemistry Hyperthyroidism Internal medicine medicine Humans Urea In patient Amino Acids Chromatography business.industry Biochemistry (medical) General Medicine medicine.disease Alkaline Phosphatase Endocrinology Kidney Tubules Hyperaminoaciduria Renal physiology Hypercalcemia Calcium Osteitis business Primary hyperparathyroidism |
| Zdroj: | Clinica chimica acta; international journal of clinical chemistry. 41 |
| ISSN: | 0009-8981 |
| Popis: | The relationship between primary hyperparathyroidism, impaired tubular reabsorption of inorganic phosphate and increased circulating parathyroid hormone is well documented. We examined urinary excretion of amino acids by Chromatographic methods in 184 patients with primary hyperparathyroidism proved at operation. One third of the patients had hyperaminoaciduria. The frequency of this finding was twice as great in patients presenting with osteitis fibrosa compared to those who present in other ways and who have normal bones. The hyperaminoaciduria is the result of impaired net tubular reabsorption, which is often reversible after removal of the overacting parathyroid tissue. The frequency of hyperaminoaciduria in a group of patients with hypercalcaemia of non-parathyroid origin was similar to that of the parathyroid group without bone disease. |
| Databáze: | OpenAIRE |
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