Circulatory effects of enflurane in normocarbic human volunteers
| Autor: | Veronica Nanagas, Paul R. Levesque, Carolyn Shanks, Shiro Shimosato |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Adult
Male Methyl Ethers medicine.medical_specialty Cardiac output Diastole Hemodynamics Enflurane Heart Rate Anesthesiology Internal medicine Heart rate medicine Humans Cardiac Output business.industry General Medicine Carbon Dioxide Hydrogen-Ion Concentration Oxygen Anesthesiology and Pain Medicine medicine.anatomical_structure Anesthesia Circulatory system Vascular resistance Cardiology Vascular Resistance business Anesthesia Inhalation medicine.drug |
| Zdroj: | Canadian Anaesthetists' Society journal. 21(6) |
| ISSN: | 0008-2856 |
| Popis: | The circulatory effects of enflurane were studied in ten unmedicated normocarbic volunteers during anaesthesia over a period of 90 minutes or more. Cardiac output did not change significantly during anaesthesia at a mean alveolar anaesthetic concentration of 2.3 volumes per cent and ranging from 1.8 to 3.2. Systolic, diastolic and mean arterial pressures decreased significantly, as did total peripheral resistance. The heart rate increased in all cases. Cardiac output was maintained primarily by an increased heart rate, which compensated for the decreased total peripheral resistance. At recovery, all haemodynamic parameters except heart rate returned to control levels. Minimal change in cardiac output during enflurane anaesthesia in man may be related to the combination of decreased mean arterial pressure and increased heart rate. |
| Databáze: | OpenAIRE |
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