The first isolation of Westerdykella dispersa in a critically burned patient
| Autor: | Matej Bezdicek, Ivan Suchánek, Pavel Brychta, Bretislav Lipovy, Jakub Holoubek, Iva Kocmanová, Markéta Hanslianová, Hana Rihova |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Male medicine.medical_specialty Antifungal Agents Isolation (health care) 030106 microbiology Thermal trauma Microbial Sensitivity Tests Microbiology 03 medical and health sciences Young Adult 0302 clinical medicine Ascomycota Internal medicine DNA Ribosomal Spacer medicine Humans Colonization Young adult DNA Fungal Pathogen Czech Republic business.industry Incidence (epidemiology) Fungal genetics Westerdykella dispersa 030208 emergency & critical care medicine General Medicine RNA Ribosomal 5.8S Treatment Outcome Mycoses business Burns |
| Zdroj: | Folia microbiologica. 63(4) |
| ISSN: | 1874-9356 |
| Popis: | Patients with critical thermal trauma belong to one of the most high-risk groups for development of infectious complications. Fungal infections are not among frequent complications during therapy of patients with thermal trauma, yet their incidence dramatically aggravates the prognosis for patients with this disorder. In the case report, we present the case of a young man with a critical burn, where Westerdykella dispersa was isolated. Identification of the pathogen was provided with a combination of cultivation and molecular biological confirmation. In this case, the distinction between infection and colonization was very complicated. Histopathological examination for definitive diagnosis of infection was not performed because the material from unburned soft tissue sampling could further compromise the function of the hand. Repeated cultivation and molecular identification W. dispersa before and after the necrectomy is indicative of infection rather than colonization. It is the second documented case of positive cultivation with this pathogen in humans and the first such case in a non-neutropenic host. |
| Databáze: | OpenAIRE |
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