Routine Chest Computed Tomography for Staging of Pancreatic Head Carcinoma

Autor: Koert P. de Jong, Dianne Leeuw, Bobby K Pranger, Joris I. Erdmann, Vincent E de Meijer, Jan Pieter Pennings
Přispěvatelé: Surgery, Guided Treatment in Optimal Selected Cancer Patients (GUTS), Groningen Institute for Organ Transplantation (GIOT), Center for Liver, Digestive and Metabolic Diseases (CLDM)
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Male
Endocrinology
Diabetes and Metabolism

THERAPY
0302 clinical medicine
Endocrinology
pancreas
PULMONARY NODULES
Netherlands
Multiple Pulmonary Nodules
Incidence
pancreatic neoplasms
solitary pulmonary nodule
Middle Aged
CANCER
medicine.anatomical_structure
030220 oncology & carcinogenesis
030211 gastroenterology & hepatology
Female
Radiography
Thoracic

Radiology
Pancreas
medicine.medical_specialty
RESECTION
Malignancy
multiple pulmonary nodules
03 medical and health sciences
Predictive Value of Tests
Pancreatic cancer
Internal Medicine
medicine
Carcinoma
x-ray computed tomography
Humans
Aged
Neoplasm Staging
Retrospective Studies
Solitary pulmonary nodule
CONSEQUENCES
Hepatology
business.industry
Cancer
Retrospective cohort study
ADENOCARCINOMA
medicine.disease
METASTASES
Health Care Surveys
PATTERNS
business
Tomography
X-Ray Computed
Zdroj: Pancreas, 49(3), 387-392. Lippincott Williams and Wilkins
PANCREAS, 49(3), 387-392. LIPPINCOTT WILLIAMS & WILKINS
ISSN: 0885-3177
Popis: ObjectivesThe diagnostic value of routine chest computed tomography (CT) in addition to abdominal CT in workup for pancreatic head carcinoma is unclear. The aim of this study was to determine if routine chest CT revealed significant lesions that altered the management of patients with suspected pancreatic head carcinoma.MethodsAll Dutch pancreatic cancer centers were surveyed on the use of chest CT in preoperative staging. In addition, a single-center retrospective cohort study was performed including all patients referred with suspected pancreatic head malignancy without chest CT between 2005 and 2016. The primary end point was the proportion of patients in which chest CT revealed clinically significant lesions, leading to a change in management.ResultsIn 7 of 18 Dutch pancreatic cancer centers (39%), a preoperative chest CT is not routinely performed. In the study cohort, 170 of 848 patients (20%) were referred without chest CT and underwent one by local protocol. Chest CT revealed new suspicious lesions in 17 patients (10%), of whom 6 had metastatic disease (3.5%).ConclusionsRoutine use of chest CT in diagnostic workup for pancreatic head carcinoma reveals clinically significant lesions in 10% of patients, being metastases in up to 4%.
Databáze: OpenAIRE