Prevalence of Gestational Fasting and Postload Single Dysglycemia in Mexican-American Women and Their Relative Significance in Identifying Carbohydrate Intolerance
| Autor: | Ramaswami Kalamegham, Zuber D. Mulla, Bahij S Nuwayhid |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty endocrine system diseases Population Blood sugar Impaired glucose tolerance Young Adult Pregnancy Glucose Metabolism Disorder Internal medicine Glucose Intolerance Mexican Americans Prevalence medicine Humans education Mexico Glucose Metabolism Disorders Retrospective Studies Glucose tolerance test education.field_of_study medicine.diagnostic_test Obstetrics business.industry nutritional and metabolic diseases Obstetrics and Gynecology Fasting Glucose Tolerance Test medicine.disease Impaired fasting glucose Pregnancy Complications Gestational diabetes Diabetes Gestational Endocrinology Pediatrics Perinatology and Child Health Female business |
| Zdroj: | American Journal of Perinatology. 27:697-704 |
| ISSN: | 1098-8785 0735-1631 |
| DOI: | 10.1055/s-0030-1253101 |
| Popis: | This study investigated the prevalence of gestational dysglycemia in a largely Hispanic population in a U.S.-Mexico border city and the influence of single plasma glucose (PG) result on the identification of gestational carbohydrate intolerance. Gestational dysglycemia was studied in a largely Mexican-American population using retrospective data. Gestational diabetes (GDM), gestational impaired fasting glucose (GIFG), and gestational impaired glucose tolerance (GIGT) were identified with Carpenter-Coustan thresholds. Glucose challenge test result was abnormal in 32.7% of 18307 women screened; 47% of them had one or more dysglycemic results in the confirmatory oral glucose tolerance test (OGTT). The prevalence of GDM, GIFG, and GIGT in these women was 8.7, 2.2, and 4.5%, respectively. Fasting, 1-hour, 2-hour, and 3-hour PGs were elevated in 20.5, 28.5, 25.0, and 15.0% of OGTT, respectively (GIFG: 6.0%; 1-hour GIGT: 6.5%; 2-hour GIGT: 4.4%; and 3-hour GIGT: 3.1%). Twelve percent of OGTTs showed dysglycemia at 1 hour with normal 2-hour PG. Isolated dysglycemia, similar to GDM, is prevalent in Mexican-American women. The minimal impact of 3-hour PG supports a 2-hour OGTT. But our results question the use of an "OGTT protocol without a first-hour specimen." |
| Databáze: | OpenAIRE |
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