Gluconeogenesis, non-essential amino acid synthesis and substrate partitioning in chicken embryos during later development
| Autor: | Brian J. Bequette, Umang Agarwal, Q. Hu |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
animal structures Citric Acid Cycle Chick Embryo 03 medical and health sciences chemistry.chemical_compound Glycerol Animals Glycolysis Amino Acids Glycogen synthase biology Fatty acid metabolism Chemistry Gluconeogenesis 0402 animal and dairy science 04 agricultural and veterinary sciences General Medicine Pyruvate dehydrogenase complex 040201 dairy & animal science Pyruvate carboxylase Citric acid cycle 030104 developmental biology Biochemistry embryonic structures biology.protein Animal Science and Zoology Chickens |
| Zdroj: | Poultry Science. 96:414-424 |
| ISSN: | 0032-5791 |
| DOI: | 10.3382/ps/pew249 |
| Popis: | We aimed to quantify the rate of gluconeogenesis (GNG), non-essential amino-acid (NEAA) synthesis, and substrate partitioning to the Krebs cycle in embryonic (e) day e14 and e19 chicken embryos. An in ovo continuous tracer infusion approach was employed to test the hypotheses that GNG and NEAA synthesis in developing chicken embryo increases from e14 to e19. [13C6]Glucose or [13C3]glycerol was continuously infused (8 h) into the chorio-allantoic compartment of eggs on e14 and e19. Glucose entry rate, Cori cycling, and GNG were higher (P |
| Databáze: | OpenAIRE |
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