International AIDS Society global scientific strategy: towards an HIV cure 2016

Autor: Deeks, Sg, Lewin, Sr, Ross, Al, Ananworanich, J, Benkirane, M, Cannon, P, Chomont, N, Douek, D, Lifson, Jd, Lo, Yr, Kuritzkes, D, Margolis, D, Mellors, J, Persaud, D, Tucker, Jd, Barre-Sinoussi, F, International Aids Society Towards a Cure Working Group, International Aids Society Towards a Cure Working Group, Alter, G, Auerbach, J, Autran, B, Barouch, Dh, Behrens, G, Cavazzana, M, Chen, Z, Cohen, Ea, Corbelli, Gm, Eholié, S, Eyal, N, Fidier, S, Garcia, L, Grossman, C, Henderson, G, Henrich, Tj, Jefferys, R, Kiem, Hp, Mccune, J, Moodley, K, Newman, Pa, Nijhuis, M, Nsubuga, Ms, Ott, M, Palmer, S, Richman, D, Saez-Cirion, A, Sharp, M, Siliciano, J, Silvestri, G, Singh, J, Spire, B, Taylor, J, Tolstrup, M, Valente, S, van Lunzen, J, Walensky, R, Wilson, I, Zack, J
Přispěvatelé: Department of Medicine [San Francisco], University of California [San Francisco] (UC San Francisco), University of California (UC)-University of California (UC), The Peter Doherty Institute for Infection and Immunity [Melbourne], University of Melbourne-The Royal Melbourne Hospital, Department of Infectious Diseases, Alfred Hospital and Monash University, Melbourne, Australia, International and Scientific Relations Office, ANRS, Paris, France, Walter Reed Army Institute of Research, Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), University of Southern California (USC), Centre de Recherche du Centre Hospitalier de l’Université de Montréal (CR CHUM), Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal (UdeM)-Université de Montréal (UdeM), National Institutes of Health [Bethesda] (NIH), Frederick National Laboratory for Cancer Research (FNLCR), World Health Organization Regional Office for the Western Pacific, Manila, Philippines, Brigham and Women's Hospital [Boston], University of North Carolina [Chapel Hill] (UNC), University of North Carolina System (UNC), University of Pittsburgh School of Medicine, Pennsylvania Commonwealth System of Higher Education (PCSHE), Johns Hopkins Bloomberg School of Public Health [Baltimore], Johns Hopkins University (JHU), Institut Pasteur [Paris] (IP), Ragon Institute of MGH, MIT and Harvard, Centre d'Immunologie et de Maladies Infectieuses (CIMI), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Beth Israel Deaconess Medical Center [Boston] (BIDMC), Harvard Medical School [Boston] (HMS), Clinic for Immunology and Rhematology, Hannover Medical School, Hanover, Germany, Département de Biothérapie [CHU Necker], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5)-CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), AIDS Institute, The University of Hong Kong, Pok Fu Lam, Hong Kong, Institut de Recherches Cliniques de Montréal (IRCM), Université de Montréal (UdeM), European AIDS Treatment Group, Italy, Programme PAC-CI, Centre Hospitalier Universitaire de Treichville, Abidjan, Côte d'Ivoire, Harvard School of Public Health, Imperial College London, The B-Change Group, Manila, Philippines, Treatment Action Group (TAG), Fred Hutchinson Cancer Research Center [Seattle] (FHCRC), Stellenbosch University, Factor-Inwentash Faculty of Social Work, University of Toronto, Toronto, Ontario, Canada, University Medical Center [Utrecht], Joint Clinical Research Centre, University of California (UC), The Westmead Institute for Medical Research, University of California [San Diego] (UC San Diego), Independent HIV Education and Advocacy Consultant, San Francisco, California, USA, Emory University [Atlanta, GA], Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale (SESSTIM - U912 INSERM - Aix Marseille Univ - IRD), Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), CARE Collaboratory Community Advisory Board, Palm Springs, California, USA., Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark., The Scripps Research Institute [La Jolla, San Diego], ViiV Healthcare, London, United Kingdom., Massachusetts General Hospital [Boston], Brown University School of Public Health, David Geffen School of Medicine [Los Angeles], University of California [Los Angeles] (UCLA), University of California [San Francisco] (UCSF), University of California-University of California, Institut Pasteur [Paris], CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Descartes - Paris 5 (UPD5), Department of Medicine, Imperial College London, London, United Kingdom, University of California, Institut de Recherche pour le Développement (IRD)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU), Scripps Research Institute, Imperial College Healthcare NHS Trust- BRC Funding, American Foundation for AIDS Research, Medical Research Council (MRC), MRC DCS, British HIV Association (BHIVA), Larose, Catherine
Rok vydání: 2016
Předmět:
CD4(+) T-CELLS
0301 basic medicine
International Cooperation
[SDV]Life Sciences [q-bio]
VIRAL RESERVOIR
Human immunodeficiency virus (HIV)
Stakeholder engagement
HIV Infections
[SDV.GEN] Life Sciences [q-bio]/Genetics
Research & Experimental Medicine
medicine.disease_cause
Medicine
Societies
Medical
IN-VIVO
ComputingMilieux_MISCELLANEOUS
HIGHLY PATHOGENIC SIV
virus diseases
LATENT HIV-1
11 Medical And Health Sciences
General Medicine
TREATMENT INTERRUPTION
3. Good health
[SDV] Life Sciences [q-bio]
International AIDS Society Towards a Cure Working Group
Medicine
Research & Experimental
Goals
Life Sciences & Biomedicine
BROADLY NEUTRALIZING ANTIBODIES
Biochemistry & Molecular Biology
medicine.medical_specialty
RALTEGRAVIR INTENSIFICATION
Immunology
education
Article
General Biochemistry
Genetics and Molecular Biology
HISTONE DEACETYLASE INHIBITOR
03 medical and health sciences
Global population
Acquired immunodeficiency syndrome (AIDS)
SUPPRESSIVE ANTIRETROVIRAL THERAPY
Journal Article
Humans
Organizational Objectives
Acquired Immunodeficiency Syndrome
[SDV.GEN]Life Sciences [q-bio]/Genetics
Science & Technology
business.industry
Research
Cell Biology
medicine.disease
Antiretroviral therapy
030104 developmental biology
Treatment interruption
Family medicine
business
Zdroj: Nature Medicine
Nature Medicine, 2016, 22 (8), pp.839-850. ⟨10.1038/nm.4108⟩
Deeks, S G, Lewin, S R, Ross, A L, Ananworanich, J, Benkirane, M, Cannon, P, Chomont, N, Douek, D, Lifson, J D, Lo, Y-R, Kuritzkes, D, Margolis, D, Mellors, J, Persaud, D, Tucker, J D, Barre-Sinoussi, F, Alter, G, Auerbach, J, Autran, B, Barouch, D H, Behrens, G, Cavazzana, M, Chen, Z, Cohen, É A, Corbelli, G M, Eholié, S, Eyal, N, Fidler, S, Garcia, L, Grossman, C, Henderson, G, Henrich, T J, Jefferys, R, Kiem, H-P, McCune, J, Moodley, K, Newman, P A, Nijhuis, M, Nsubuga, M S, Ott, M, Palmer, S, Richman, D, Saez-Cirion, A, Sharp, M, Siliciano, J, Silvestri, G, Singh, J, Spire, B, Taylor, J, Tolstrup, M, Valente, S, van Lunzen, J, Walensky, R, Wilson, I & Zack, J 2016, ' International AIDS Society global scientific strategy : towards an HIV cure 2016 ', Nature Medicine, vol. 22, no. 8, pp. 839-50 . https://doi.org/10.1038/nm.4108
Nature Medicine, Nature Publishing Group, 2016, 22 (8), pp.839-850. ⟨10.1038/nm.4108⟩
ISSN: 1546-170X
1078-8956
1744-7933
DOI: 10.1038/nm.4108
Popis: Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a global population of more than 35 million people living with HIV, there is intense interest in developing a cure for HIV infection. The International AIDS Society convened a group of international experts to develop a scientific strategy for research towards an HIV cure. This Perspective summarizes the group's strategy.
Databáze: OpenAIRE
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