A rare case of enteropathy-associated T-cell lymphoma presenting as acute renal failure
| Autor: | Milena Bakrac, Sanja Simic, Miodrag Krstic, Milica Colovic, Branka Bonaci |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
Pathology medicine.medical_specialty medicine.medical_treatment Fulminant Case Report Laparotomy Intestinal Neoplasms Biopsy medicine Humans Common bile duct medicine.diagnostic_test business.industry Gastroenterology Acute kidney injury Lymphoma T-Cell Peripheral General Medicine Acute Kidney Injury medicine.disease Lymphoma Celiac Disease medicine.anatomical_structure Enteropathy-associated T-cell lymphoma Female business Nephritis |
| Zdroj: | World Journal of Gastroenterology. 12:2301 |
| ISSN: | 1007-9327 |
| DOI: | 10.3748/wjg.v12.i14.2301 |
| Popis: | Enteropathy-associated T-cell lymphoma (EATCL) is a high grade, pleomorphic peripheral T-cell lymphoma usually with cytotoxic phenotypes. We describe a first case of patient with EATCL that is remarkable for its fulminant course and invasion of both kidneys manifested as acute renal failure. The patient was a 23 year old woman with a long history of celiac disease. She was presented with acute renal failure and enlarged mononuclear infiltrated kidneys. Diagnosis of tubuloi-nterstitial nephritis and polyserositis was confirmed with consecutive pulse doses of steroid therapy. After reco-very, she had disseminated disease two months later. Magnetic resonance imaging showed thickened intestine wall, extremely augmented kidneys, enlarged intra-abdominal lymph nodes with extra-luminal compression of common bile duct. Laparotomy with mesenterial adipous tissue and lymph glands biopsy was done. Consecutive pathophysiological and immunohistochemical analyses confirmed the diagnosis of EATCL: CD45RO+, CD43+, CD3+. The revision of renal pathophysiology sub-stantiated the diagnosis. The patient received chemotherapy, but unfortunately she died manifesting signs of pulmonary embolism caused by tumor cells. |
| Databáze: | OpenAIRE |
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