Anaesthesia of the posterior urethra and pain reduction during cystoscopy - a randomized controlled trial
| Autor: | Piotr Radziszewski, Marcin Łykowski, Sławomir Poletajew, Sylwia Bender, Bartosz Sutkowski, Paweł Pudełko, Tomasz Piecha |
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| Rok vydání: | 2016 |
| Předmět: |
Lidocaine
Urology Urinary system law.invention Urology: Original paper Randomized controlled trial law Clinical endpoint medicine cystoscopy Bladder cancer medicine.diagnostic_test business.industry Gastroenterology Obstetrics and Gynecology Cystoscopy anaesthesia medicine.disease Urethra medicine.anatomical_structure Anesthesia Relative risk bladder cancer Surgery urethra business medicine.drug |
| Zdroj: | Videosurgery and other Miniinvasive Techniques |
| ISSN: | 1895-4588 |
| Popis: | INTRODUCTION Standard intra-urethral instillation of anaesthetic gel may not sufficiently exclude pain perception during cystoscopy. AIM To evaluate the impact of the anaesthesia within the posterior urethra on pain intensity related to cystoscopy in men. MATERIAL AND METHODS One hundred and twenty-seven men undergoing cystoscopy were prospectively enrolled in the study. Patients were randomly assigned to the experimental or control group (66 vs. 61 patients). Intra-urethral instillation of 2% lidocaine gel was done in both groups. In the experimental group, the posterior urethra was additionally anaesthetized with distribution of the lidocaine gel by catheterisation. The study endpoints were pain intensity at successive time points of the procedure assessed on a numeric rating scale, overall pain intensity assessed on a Likert scale, the need for analgesics during 6 h after the procedure, and the frequency of urinary tract infections (UTIs) during 14 days after the procedure. RESULTS Pain perception during cystoscopy did not differ significantly between the two groups (p > 0.05). However, after 6 h patients in the experimental group were more likely to declare that the cystoscopy was painless (81.8% vs. 70.2%, relative risk = 1.17). The need for analgesics and the incidence of UTI were similar in both groups (p > 0.05). Statistically significant differences regarding pain perception were observed depending on patients' age and the number of transurethral procedures performed in the past, with no relation to type of anaesthesia (p < 0.05). CONCLUSIONS Anaesthesia of the posterior urethra is not more efficacious in reducing pain related to cystoscopy than standard instillation of anaesthetic gel. However, it improves the general perception of the procedure, and hence may positively influence patients' compliance. |
| Databáze: | OpenAIRE |
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