Revisit of risk factors for major obstetric hemorrhage: insights from a large medical center
| Autor: | Sorina Grisaru-Granovsky, Rivka Farkash, Hila Fruchtman, Alexander Ioscovich, Sarit Helman, Arnon Samueloff, Tehila Avitan, Lior Drukker |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Psychological intervention Hysterectomy Single Center Logistic regression Severity of Illness Index Instrumental delivery Pregnancy Risk Factors Odds Ratio Humans Medicine Blood Transfusion Retrospective Studies Cesarean Section business.industry Obstetrics Postpartum Hemorrhage Pregnancy Outcome Case-control study Obstetrics and Gynecology General Medicine Odds ratio Delivery Obstetric Obstetric Labor Complications Logistic Models Maternal Mortality Case-Control Studies Multivariate Analysis Female Electronic database business |
| Zdroj: | Archives of Gynecology and Obstetrics. 292:819-828 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-015-3725-y |
| Popis: | To revisit risk factors of major obstetric hemorrhage in a large obstetric center. A retrospective case control study was conducted based on institutional electronic database and blood bank registry of a single center, 2005–2014. The major obstetric hemorrhage event was defined as transfusion of ≥5 red blood cells units within 48 h of birth and compared to matched group (ratio 1:4) based on the time of birth. Multivariable stepwise backward logistic regression models were fitted to determine risk factors for major obstetric hemorrhage. Odds ratio (OR), further evaluated by standard measures of the predictive accuracy of the logistic regression models, C statistics, and associated neonatal adverse outcome are reported. 113,342 women delivered during the study; 122 (0.1 %) women experienced major obstetric hemorrhage. There was one major obstetric hemorrhage fatality (0.8 %). Compared to the controls, we identified historical as well as significant current modifiable risk factors for major obstetric hemorrhage: multifetal pregnancy (OR 3.92; 95 % CI 1.34–11.52; p = 0.013), induction of labor (OR 2.81; 95 % CI 1.22–7.05; p = 0.027), cesarean section (OR 25.56; 95 % CI 12.88–50.75; p |
| Databáze: | OpenAIRE |
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