Blood glutathione levels in head and neck malignancies
| Autor: | O. P. Sachdeva, Harbans Lal, Y. P. Singh, S Aggarwal, Kiran Chugh |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.medical_specialty
Pathology business.industry medicine.medical_treatment Clinical Biochemistry Head and neck cancer Glutathione medicine.disease medicine.disease_cause Gastroenterology Article Radiation therapy Lesion chemistry.chemical_compound chemistry Internal medicine medicine In patient Histopathology medicine.symptom business Head and neck Oxidative stress |
| Zdroj: | Indian Journal of Clinical Biochemistry. 23:290-292 |
| ISSN: | 0974-0422 0970-1915 |
| Popis: | Blood glutathione was estimated in fifty patients of head and neck cancer in the age group of 18–76 years and the results were compared with a group of normal healthy controls. Mean blood glutathione level was found to be significantly lowered in patients than the controls. Irrespective of the site, TNM classification, histopathology, and character of lesion, fall in blood glutathione was nearly same in all the patients. The mean level was significantly increased after radiotherapy when compared with the levels before radiotherapy. The decreased levels of GSH in-patients with head and neck cancer, observed in the present study, may be due to its increased utilization by the cells. The results suggest that patients with head and neck cancer have increased oxidative stress. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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